关于 "Aldehyde dehydrogenase" 的结果36+ 个结果
筛选:Proteases×
- GSK 2837808ACAS: 1445879-21-9
GSK2837808A 是一种选择性的 LDHA (lactate dehydrogenase A) 的抑制剂,对hLDHA和hLDHB的IC50分别为2.6 nM和43 nM.GSK2837808A(10 µM;24-72h)通过促进有氧糖酵解、增殖、细胞周期和细胞凋亡抵抗,阻断了着丝粒蛋白N (CENP-N)过表达对鼻咽癌细胞的影响。
- D-(-)-Lactic acidCAS: 10326-41-7
D-(-)-Lactic acid 是糖发酵 (氧化，新成代谢) 的一个中间产物。D-(-)-Lactic acid 在植物中是 ProDH (proline dehydrogenase 1)) 的竞争性抑制剂。
- (E)-Oct-2-enoic acidCAS: 1871-67-6
2-Octenoic acid (2-Octenoate) is a normal organic acid produced by hepatic microsomal oxidation of aliphatic aldehydes and is a metabolite naturally found in the urine and plasma.
- GSK864CAS: 1816331-66-4
GSK864是一种突变型isocitrate dehydrogenases 1 (mIDH1)抑制剂，对IDH1 R132H、IDH1 R132C及WT IDH1的EC 50 值分别为0.16μM、0.10μM和2.74μM。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC13464 | GSK 2837808A | 1445879-21-9 | Lactate Dehydrogenase | ||
GSK2837808A 是一种选择性的 LDHA (lactate dehydrogenase A) 的抑制剂,对hLDHA和hLDHB的IC50分别为2.6 nM和43 nM.GSK2837808A(10 µM;24-72h)通过促进有氧糖酵解、增殖、细胞周期和细胞凋亡抵抗,阻断了着丝粒蛋白N (CENP-N)过表达对鼻咽癌细胞的影响。 | |||||
| GC35794 | D-(-)-Lactic acid | 10326-41-7 | Endogenous Metabolite | ||
D-(-)-Lactic acid 是糖发酵 (氧化，新成代谢) 的一个中间产物。D-(-)-Lactic acid 在植物中是 ProDH (proline dehydrogenase 1)) 的竞争性抑制剂。 | |||||
| GC62734 | (E)-Oct-2-enoic acid | 1871-67-6 | Endogenous Metabolite | ||
2-Octenoic acid (2-Octenoate) is a normal organic acid produced by hepatic microsomal oxidation of aliphatic aldehydes and is a metabolite naturally found in the urine and plasma. | |||||
| GC10531 | AGI-5198 | 1355326-35-0 | Isocitrate Dehydrogenase (IDH) | ||
A potent, selective inhibitor of IDH1 mutations | |||||
| GC14757 | AGI-6780 | 1432660-47-3 | Isocitrate Dehydrogenase (IDH) | ||
A potent, selective inhibitor of mutant IDH2 | |||||
| GC17809 | GSK864 | 1816331-66-4 | Isocitrate Dehydrogenase (IDH) | ||
GSK864是一种突变型isocitrate dehydrogenases 1 (mIDH1)抑制剂，对IDH1 R132H、IDH1 R132C及WT IDH1的EC50值分别为0.16μM、0.10μM和2.74μM。 | |||||
| GC40265 | Pheleuin | 169195-23-7 | Proteolysis | ||
A pyrazinone | |||||
| GC13670 | Methylmalonate | 516-05-2 | Endogenous Metabolite | ||
A dicarboxylic acid and byproduct of propionate catabolism | |||||
| GC13147 | AG-221 (Enasidenib) | 1446502-11-9 | Isocitrate Dehydrogenase (IDH) | ||
An inhibitor of mutant IDH2 | |||||
| GC19380 | Vorasidenib | 1644545-52-7 | Isocitrate Dehydrogenase (IDH) | ||
An inhibitor of mutant IDH1 and IDH2 | |||||
| GC19059 | BAY-1436032 | 1803274-65-8 | Isocitrate Dehydrogenase (IDH) | ||
An inhibitor of mutant IDH1 | |||||
| GC44793 | Pyrroloquinoline quinone | 72909-34-3 | Endogenous Metabolite | ||
据报道，吡咯并喹啉醌是一种新的哺乳动物乳酸脱氢酶 (LDH) 辅酶。 | |||||