关于 "Cytoskeleton & Motor Proteins" 的结果84+ 个结果

Low molecular weight protamine (LMWP) is a peptide fragment produced in our laboratory from enzymatic digestion of native protamine.

髓鞘碱性蛋白 MBP (MHP4-14) 是一种包含髓鞘碱性蛋白残基 4-14 的合成肽，是一种非常具有选择性的 PKC 底物 (Km=7 μM)。

PrP(106-126)是与朊病毒蛋白的淀粉样区域相对应的多肽段，它的生化特性类似于朊病毒蛋白的感染区域。

淀粉样蛋白 β-蛋白 (1-15) 是 β-淀粉样蛋白肽的片段。

Amyloid β-Protein (16-20)是一种β-淀粉样蛋白的五个氨基酸片段。

Protein Kinase C (19-31)是蛋白激酶 C (PKC)的抑制剂,是由 PKCa (残基 19-31) 伪底物调控域衍生而来，25 位丝氨酸取代野生型丙氨酸作为蛋白激酶 C 底物肽，用于检测蛋白激酶 C 的活性。Protein kinase C (PKC) 通过磷酸化丝氨酸和苏氨酸氨基酸残基上的羟基来调控其它蛋白的功能。

G-蛋白拮抗肽是抑制G蛋白与其受体结合的P物质相关肽。

Tauprotein(592-597),Human(TFA)是人Tau蛋白的多肽片段。Tau蛋白功能紊乱与神经退化和痴呆有关系。

Amyloid β-protein (10-35), YEVHHQKLVFFAEDVGSNKGAIIGLM, was used as a truncated peptide model for the full-length amyloid β-proteins (1-40) and (1-42) in high-resolution structural studies. In contrast to the full-length amyloid β-proteins, amyloid β-protein (10-35) allowed the controlled and reproducible formation of homogeneous fibrils from aqueous solutions of defined pH, ionic strength and soluble peptide concentration necessary for high-resolution structural studies.

The N-terminal Aβ fragments Aβ1-14, Aβ1-15 (H-6368), and Aβ1-16 (H-2958) are elevated in cell media and in CSF in response to γ-secretase inhibitor treatment. The presence of these small peptides is consistent with a catabolic amyloid precursor protein cleavage pathway by β- followed by α-secretase. It has been shown that Aβ1-14, Aβ1-15, and Aβ1-16 increase dose-dependently in response to γ-secretase inhibitor treatment while Aβ1-42 levels are unchanged.

淀粉样蛋白 β-蛋白质 (1-37) 与阿尔茨海默病的简易精神状态检查 (MMSE) 评分中度相关。

Like Aβ (25-35) (H-1192), the Aβ fragment (1-38) destabilizes calcium homeostasis and renders human cortical neurones vulnerable to environmental insults.

Small quantities of Aβ37, 38 and 39 can be detected in CSF together with Aβ40, the most abundant Aβ homolog, Aβ42, and N-terminally truncated amyloid peptides. The relative amounts depend on the variant of Alzheimer's disease. The C-terminally truncated amyloid peptides are also found in amyloid plaques.

淀粉样蛋白 β-Protein (1-43) 比久负盛名的 Aβ1-42 更容易聚集并具有更高的毒性。

Precursor of the secreted amyloid β-protein (1-40) and (1-42). The identification of amyloid-β-protein (1-46) led to the identification of a zeta-cleavage site between the known γ- and ε-cleavage sites within the transmembrane domain of amyloid-β precursor protein (APP).

Self-assembling Aβ sequence.

Cleavage of APP by alpha- and gamma-secretase (i.e. the non-amyloidogenic pathway) yields p3 peptide, a mix of Aβ 17-40 and Aβ 17-42. p3 is a major constituent of diffuse plaques observed in AD brains and pre-amyloid plaques in people affected by Down syndrome.

FAEDVGSNKG.

GLMVGGVVIA, a partial sequence of β-amyloid protein which is used for raising antibodies against Aβ 1-42. Li et al. studied the aggregation behavior of this and other Aβ 1-42 C-terminal fragments.

Aβ 25-35 的反向序列，非活性对照。