关于 "NADPH Oxidase" 的结果27+ 个结果
- APX-115 free baseCAS: 1270084-92-8
Isuzinaxib (APX-115 free base, Ewha-18278 free base) is a potent, orally active inhibitor of pan NADPH oxidase (pan-Nox) with Ki of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 free base (Ewha-18278 free base) significantly suppresses the expression of inflammatory molecules including MCP-1/CCL2, IL-6, and TNFα in the diabetic kidney.
- Glycolic acid oxidase inhibitor 1CAS: 77529-42-1
Glycolicacidoxidaseinhibitor1是一种乙醇酸氧化酶(glycolateoxidase)抑制剂，详细信息请参考专利文献EP0021228A1中Table1中的第2个化合物。
Others - GKT137831CAS: 1218942-37-0
GKT137831是一种口服有效的双重NADPH氧化酶1/4（NOX1/NOX4）抑制剂，活性处于亚微摩尔范围，可预防高糖诱导的人主动脉内皮细胞氧化应激，并减轻糖尿病小鼠的动脉粥样硬化进展。
- DAAO inhibitor-1CAS: 2065250-25-9
KUN50259 (DAAO inhibitor-1, Compound 35) is a potent inhibitor of D-amino acid oxidase (DAAO) with an IC50 of 0.12 μM.
Others - NADP disodium salt (Disodium NADP)CAS: 24292-60-2
Triphosphopyridine nucleotide (NADP) serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).
Others - Diphenyleneiodonium chlorideCAS: 4673-26-1
二苯碘铵 (DPI) 氯化物 (DPIC) 作为 NADH/NADPH 氧化酶抑制剂，对 Mtb 和 S. aureus 具有有效的抗菌活性。
- OxyfluorfenCAS: 42874-03-3
Oxyfluorfen 是一种出苗前和出苗后的二苯醚除草剂，以控制一年生阔叶杂草和草类杂草。Oxyfluorfen 是原卟啉原氧化酶 (protoporphyrinogen oxidase) 抑制剂，可通过阻止叶绿素合成来抑制光合作用。
Others
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC71188 | NADPH oxidase-IN-1 | 2762405-17-2 | NADPH Oxidase | ||
NADPH oxidase-IN-1是一种与神经元炎症相关的口服活性NADPH氧化酶（Nox）抑制剂。 | |||||
| GC32443 | VAS2870 | 722456-31-7 | NADPH Oxidase | ||
A pan-NADPH oxidase inhibitor | |||||
| GC38115 | APX-115 free base | 1270084-92-8 | NADPH Oxidase | ||
Isuzinaxib (APX-115 free base, Ewha-18278 free base) is a potent, orally active inhibitor of pan NADPH oxidase (pan-Nox) with Ki of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 free base (Ewha-18278 free base) significantly suppresses the expression of inflammatory molecules including MCP-1/CCL2, IL-6, and TNFα in the diabetic kidney. | |||||
| GC31381 | Glycolic acid oxidase inhibitor 1 | 77529-42-1 | Others | ||
Glycolicacidoxidaseinhibitor1是一种乙醇酸氧化酶(glycolateoxidase)抑制剂，详细信息请参考专利文献EP0021228A1中Table1中的第2个化合物。 | |||||
| GC31367 | GLX351322 | 835598-94-2 | NADPH Oxidase | ||
GLX351322是一种NADPH氧化酶4 (NOX4)抑制剂，IC50值为5μM。 | |||||
| GC32681 | GSK2795039 | 1415925-18-6 | Other Apoptosis | ||
GSK2795039是一种强效NADPH氧化酶2（NOX2）抑制剂，IC50值为0.18μM。 | |||||
| GC16237 | Apocynin | 498-02-2 | Other Apoptosis | ||
Apocynin是一种天然存在的苯乙酮类化合物，可作为NADPH氧化酶复合物的强效抑制剂，IC50值为10μM。 | |||||
| GC36688 | NADP sodium salt | 1184-16-3 | Others | ||
The oxidized form of NADPH | |||||
| GC15322 | Allopurinol | 315-30-0 | Xanthine Oxidase | ||
Inhibitor of xanthine oxidase | |||||
| GC12291 | ML 171 | 6631-94-3 | NADPH Oxidase | ||
A selective, cell-active Nox1 inhibitor | |||||
| GC12323 | ML-090 | 531-46-4 | NADPH Oxidase | ||
A selective NOX1 inhibitor | |||||
| GC11882 | GKT137831 | 1218942-37-0 | Ferroptosis | ||
GKT137831是一种口服有效的双重NADPH氧化酶1/4（NOX1/NOX4）抑制剂，活性处于亚微摩尔范围，可预防高糖诱导的人主动脉内皮细胞氧化应激，并减轻糖尿病小鼠的动脉粥样硬化进展。 | |||||
| GC10827 | Oxipurinol | 2465-59-0 | Xanthine Oxidase | ||
An inhibitor of xanthine oxidase and active metabolite of allopurinol | |||||
| GC64909 | AS057278 | 402-61-9 | Others | ||
AS057278 (3-Methylpyrazole-5-carboxylic acid, MPC) is an inhibitor of D-amino acid oxidase (DAAO). | |||||
| GC50281 | NoxA1ds | 1435893-78-9 | NADPH Oxidase | ||
NoxA1ds 是一种高效和选择性的 Nox1（NADPH 氧化酶异构体 1）抑制剂。 | |||||
| GC16319 | Febuxostat | 144060-53-7 | Xanthine Oxidase | ||
An inhibitor of the oxidized and reduced forms of xanthine oxidase | |||||
| GC34554 | DAAO inhibitor-1 | 2065250-25-9 | Others | ||
KUN50259 (DAAO inhibitor-1, Compound 35) is a potent inhibitor of D-amino acid oxidase (DAAO) with an IC50 of 0.12 μM. | |||||
| GC33557 | NADP disodium salt (Disodium NADP) | 24292-60-2 | Others | ||
Triphosphopyridine nucleotide (NADP) serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). | |||||
| GC12520 | Diphenyleneiodonium chloride | 4673-26-1 | Reactive Oxygen Species | ||
二苯碘铵 (DPI) 氯化物 (DPIC) 作为 NADH/NADPH 氧化酶抑制剂，对 Mtb 和 S. aureus 具有有效的抗菌活性。 | |||||
| GC63133 | Oxyfluorfen | 42874-03-3 | Others | ||
Oxyfluorfen 是一种出苗前和出苗后的二苯醚除草剂，以控制一年生阔叶杂草和草类杂草。Oxyfluorfen 是原卟啉原氧化酶 (protoporphyrinogen oxidase) 抑制剂，可通过阻止叶绿素合成来抑制光合作用。 | |||||
| GC15529 | HQNO | 341-88-8 | Oxygenases/Oxidases | ||
A respiratory chain inhibitor | |||||
| GC10545 | MDL 72527 dihydrochloride | 93565-01-6 | Oxygenases/Oxidases | ||
MDL 72527 dihydrochloride是一种有效的多胺氧化酶（PAO）抑制剂。 | |||||
| GC17900 | Carbazeran citrate | 153473-94-0 | Oxygenases/Oxidases | ||
An inhibitor of PDE2 and PDE3 | |||||
| GC14469 | Pirlindole mesylate | 207572-66-5 | Heme oxygenase | ||
A selective and reversible MAO-A inhibitor | |||||