关于 "Cancer stem cell" 的结果38+ 个结果
- Cancer-Targeting Compound 1CAS: 1007581-62-5
Cancer-TargetingCompound1可用于与激素相关的癌症研究，摘自专利WO2008021331A2。
Others - NFAT Inhibitor (cell-permeable) (trifluoroacetate salt)
A cell-permeable form of NFAT inhibitor
- HPFCAS: 359010-69-8
A cell permeable, fluorescent dye for detection of highly reactive oxygen species
- CH 223191CAS: 301326-22-7
CH 223191是一种有效且特异性的芳烃受体（AhR）拮抗剂，可抑制TCDD介导的AhR核转位和DNA结合，并抑制TCDD诱导的荧光素酶活性，IC50为0.03 μM。
- ZINC05007751CAS: 591239-68-8
ZINC05007751 is a potent NIMA-related kinase NEK6 inhibitor with an IC50 of 3.4 μM, shows antiproliferative activity against a panel of human cancer cell lines and displays a synergistic effect with Cisplatin and Paclitaxel in a BRCA2 mutated ovarian cancer cell line. DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.
Others - CurzereneCAS: 17910-09-7
Curzerene, a sesquiterpene isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity, inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression and induces cell apoptosis.
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC17468 | ML 239 | 1378872-36-6 | Others | ||
An inhibitor of breast cancer stem cells | |||||
| GC33138 | Cancer-Targeting Compound 1 | 1007581-62-5 | Others | ||
Cancer-TargetingCompound1可用于与激素相关的癌症研究，摘自专利WO2008021331A2。 | |||||
| GC14898 | Tie2 kinase inhibitor | 948557-43-5 | Others | ||
Tie2 kinase inhibitor是一种可逆的选择性Tie2抑制剂，IC50为250 nM。 | |||||
| GC20118 | Cell-Tracker Orange CMTMR | 323192-14-9 | Fluorescence | ||
| GC50177 | Cell Activation Cocktail 500X | - | Others | ||
Cell activation cocktail | |||||
| GC52384 | NFAT Inhibitor (cell-permeable) (trifluoroacetate salt) | - | Bone Growth & Remodeling | ||
A cell-permeable form of NFAT inhibitor | |||||
| GC91154 | 33-BCRP Inhibitor | - | Apoptosis | ||
一种BCRP抑制剂 | |||||
| GC17248 | StemRegenin 1 (hydrochloride) | 2319882-01-2 | AhR | ||
Antagonizes hematopoietic stem cell differentiation | |||||
| GC15647 | ID-8 | 147591-46-6 | DYRK | ||
A cell culture supplement for maintaining embryonic stem cell pluriotency | |||||
| GC10171 | Puromycin aminonucleoside | 58-60-6 | Aminopeptidase | ||
A glomerular epithelial cell toxin | |||||
| GC17839 | Stauprimide | 154589-96-5 | Autophagy | ||
Primes stem cells for differentiation | |||||
| GC12811 | BRD7116 | 329059-55-4 | Others | ||
A selective inhibitor of leukemia stem cells | |||||
| GC43870 | HPF | 359010-69-8 | Reactive Oxygen Species | ||
A cell permeable, fluorescent dye for detection of highly reactive oxygen species | |||||
| GC15123 | IDE 1 | 1160927-48-9 | Others | ||
An inducer of definitive endoderm from embryonic stem cells | |||||
| GC91592 | CP-4 | 2569194-72-3 | Labeling & Detection | ||
CP-4 is a fluorescent probe for mesenchymal stem cells. | |||||
| GC16220 | CH 223191 | 301326-22-7 | Aryl Hydrocarbon Receptor | ||
CH 223191是一种有效且特异性的芳烃受体（AhR）拮抗剂，可抑制TCDD介导的AhR核转位和DNA结合，并抑制TCDD诱导的荧光素酶活性，IC50为0.03 μM。 | |||||
| GC18901 | CAY10647 | 1253697-49-2 | MDR multidrug resistance | ||
An inhibitor of tubulin polymerization and cancer cell growth | |||||
| GC12040 | L-Kynurenine | 2922-83-0 | Endogenous Metabolite | ||
L-Kynurenine是L-色氨酸的代谢物，也是一种芳香烃受体 (aryl hydrocarbon receptor; AhR) 激动剂。 | |||||
| GC63626 | ZINC05007751 | 591239-68-8 | Others | ||
ZINC05007751 is a potent NIMA-related kinase NEK6 inhibitor with an IC50 of 3.4 μM, shows antiproliferative activity against a panel of human cancer cell lines and displays a synergistic effect with Cisplatin and Paclitaxel in a BRCA2 mutated ovarian cancer cell line. DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation. | |||||
| GC35759 | Curzerene | 17910-09-7 | Gutathione S-transferase | ||
Curzerene, a sesquiterpene isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity, inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression and induces cell apoptosis. | |||||
| GC34150 | INH154 | 1587705-63-2 | Others | ||
INH154 is a potent inhibitor of Nek2 and Hec1 binding. NH154 binds to Hec1, thus blocking Hec1 phosphorylation by NEK2, and kills cancer cells at the nanomolar range. | |||||
| GC17043 | StemRegenin 1 (SR1) | 1227633-49-9 | Aryl Hydrocarbon Receptor | ||
StemRegenin 1 (SR1)是一种强效芳香烃受体（AhR）拮抗剂（IC50 = 127nM）。 | |||||
| GC32756 | EC330 | 2016795-77-8 | Others | ||
EC330 is a steroidal inhibitor of leukemia inhibitory factor (LIF, an interleukin 6 class cytokine). EC330 inhibits the LIF/LIF-R signaling and blocks the promoting effects of LIF on growth and migration of cancer cells. | |||||
| GC14967 | MeBIO | 667463-95-8 | AhR | ||
A control analog of BIO | |||||