关于 "Aldehyde dehydrogenase" 的结果17+ 个结果
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- 2,2-Dihydroxy-1-phenylethan-1-oneCAS: 1075-06-5
Phenylglyoxal (1-Phenylethanedione) is a potent inhibitor of mitochondrial aldehyde dehydrogenase. It reacts with arginine residues in purified Hageman factor (HF, Factor XII) and causes inhibition of its coagulant properties.
Others - Sorbitol dehydrogenase-IN-1CAS: 300551-49-9
Sorbitol dehydrogenase-IN-1是一种强效的口服活性山梨糖醇脱氮酶抑制剂，对大鼠和人类的IC50分别为4、5 nM。
Others - 8(Z),11(Z),14(Z)-HeptadecatrienalCAS: 56797-44-5
8(Z),11(Z),14(Z)-Heptadecatrienal is a polyunsaturated fatty aldehyde.
- Trans-2-HexenalCAS: 6728-26-3
Trans-2-hexenal (Leaf aldehyde) is an α,β-unsaturated carbonyl compound protecting plants against harmful substances.
Others - DCACAS: 2156-56-1
DCA 是癌细胞中的代谢调节剂'；具有抗癌活性的线粒体。 DCA 抑制 PDHK，导致肿瘤微环境中的乳酸减少。 DCA 增加活性氧 (ROS) 生成并促进癌细胞凋亡。 DCA 也可作为 NKCC 抑制剂。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC60456 | 2,2-Dihydroxy-1-phenylethan-1-one | 1075-06-5 | Others | ||
Phenylglyoxal (1-Phenylethanedione) is a potent inhibitor of mitochondrial aldehyde dehydrogenase. It reacts with arginine residues in purified Hageman factor (HF, Factor XII) and causes inhibition of its coagulant properties. | |||||
| GC72894 | Sorbitol dehydrogenase-IN-1 | 300551-49-9 | Others | ||
Sorbitol dehydrogenase-IN-1是一种强效的口服活性山梨糖醇脱氮酶抑制剂，对大鼠和人类的IC50分别为4、5 nM。 | |||||
| GC13760 | TC HSD 21 | 330203-01-5 | Others | ||
An inhibitor of 17β-HSD3 | |||||
| GC91658 | 8(Z),11(Z),14(Z)-Heptadecatrienal | 56797-44-5 | Pesticides | ||
8(Z),11(Z),14(Z)-Heptadecatrienal is a polyunsaturated fatty aldehyde. | |||||
| GC14783 | Trilostane | 13647-35-3 | Others | ||
A 3β-hydroxysteroid dehydrogenase inhibitor | |||||
| GC17914 | Fomepizole | 7554-65-6 | Others | ||
An alcohol dehydrogenase inhibitor | |||||
| GC63236 | Trans-2-Hexenal | 6728-26-3 | Others | ||
Trans-2-hexenal (Leaf aldehyde) is an α,β-unsaturated carbonyl compound protecting plants against harmful substances. | |||||
| GC36396 | KPLH1130 | 906669-07-6 | PDHK | ||
KPLH1130 is a specific inhibitor of pyruvate dehydrogenase kinase (PDK) that blocks macrophage polarization and attenuates proinflammatory responses. | |||||
| GC16795 | DCA | 2156-56-1 | Other Apoptosis | ||
DCA 是癌细胞中的代谢调节剂'；具有抗癌活性的线粒体。 DCA 抑制 PDHK，导致肿瘤微环境中的乳酸减少。 DCA 增加活性氧 (ROS) 生成并促进癌细胞凋亡。 DCA 也可作为 NKCC 抑制剂。 | |||||
| GC17900 | Carbazeran citrate | 153473-94-0 | Oxygenases/Oxidases | ||
An inhibitor of PDE2 and PDE3 | |||||
| GC17467 | Gimeracil | 103766-25-2 | Others | ||
A DYPD inhibitor | |||||
| GC17919 | Teriflunomide | 108605-62-5 | Others | ||
特立氟胺是来氟米特的活性代谢物，来氟米特是一种获准治疗类风湿性关节炎的药物。 | |||||
| GC50180 | BMS 566419 | 566161-24-8 | Others | ||
BMS 566419 是一种基于吖啶酮的肌苷 5'-单磷酸脱氢酶 (IMPDH) 抑制剂。 | |||||
| GC16860 | NCT-502 | 1542213-00-2 | Others | ||
A PHGDH inhibitor | |||||
| GC10718 | PF 915275 | 857290-04-1 | Others | ||
PF 915275 是一种有效的、选择性的、具有口服活性的人 11β-羟基类固醇脱氢酶 1 型 (11βHSD1) 抑制剂，Ki 为 2.3 nM，EC50 为 15 nM（在 HEK293 细胞中）。 | |||||
| GC19494 | ML-390 | 2029049-79-2 | Others | ||
A DHODH inhibitor | |||||
| GC50280 | JX 06 | 729-46-4 | PDHK | ||
An irreversible PDHK inhibitor | |||||