关于 "Sigma Receptor" 的结果46+ 个结果
- (Ala1)-PAR4 (1-6) amide (mouse) (trifluoroacetate salt)
A peptide agonist of PAR4
- Pridopidine (ACR16)CAS: 346688-38-8
Pridopidine (ACR16, ASP2314, FR310826) , a dopamine (DA) stabilizer, acts as an antagonist against sigma 1 receptor (S1R) and dopamine D2 receptor (D2R).
- AmitriptylineCAS: 50-48-6
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.
- OPC-14523 hydrochlorideCAS: 145969-31-9
OPC-14523 hydrochloride 是一种具有口服活性的 sigma 和 5-HT1A 受体激动剂，对 sigma 受体 (σ1/2 IC50=47/56 nM)、5-HT1A 受体 (IC50=2.3 nM) 和 5-HT 转运体 (IC50=80 nM) 具有高度亲和力。OPC-14523 hydrochloride 显示抗抑郁药样活性。
- (R)-3,4-DCPGCAS: 201730-10-1
AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors
- Batefenterol (GSK961081)CAS: 743461-65-6
A muscarinic receptor antagonist and β 2 -adrenergic receptor agonist
- Promazine hydrochlorideCAS: 53-60-1
Promazine (Romtiazin, Sinophenin) is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors with antipsychotic effects.
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC36582 | Men 10376 TFA | - | Peptides | ||
An NK2 receptor antagonist | |||||
| GC40159 | PAR1 (1-6) (mouse, rat) (trifluoroacetate salt) | - | Innate Immunity | ||
A peptide agonist of PAR1 | |||||
| GC41697 | (Ala1)-PAR4 (1-6) amide (mouse) (trifluoroacetate salt) | - | Immunology/Inflammation | ||
A peptide agonist of PAR4 | |||||
| GC91621 | WLB-89462 | 2849471-75-4 | Alzheimer | ||
WLB-89462 is a ligand of sigma intracellular receptor 2 (σ2 receptor). | |||||
| GC30854 | Pridopidine (ACR16) | 346688-38-8 | Dopamine Receptor | ||
Pridopidine (ACR16, ASP2314, FR310826) , a dopamine (DA) stabilizer, acts as an antagonist against sigma 1 receptor (S1R) and dopamine D2 receptor (D2R). | |||||
| GC25060 | Amitriptyline | 50-48-6 | Histamine Receptor | ||
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid. | |||||
| GC16937 | Carbamoylcholine chloride | 51-83-2 | nAChR | ||
Cholinergic receptor agonist | |||||
| GC17256 | Pilocarpine HCl | 54-71-7 | mAChR | ||
A muscarinic acetylcholine receptor agonist | |||||
| GC11714 | Prucalopride | 179474-81-8 | 5-HT Receptor | ||
A selective 5-HT4 receptor agonist | |||||
| GC10219 | AF-DX 116 | 102394-31-0 | mAChR | ||
A muscarinic M2 receptor antagonist | |||||
| GC15016 | SKF 83566 hydrobromide | 108179-91-5 | Dopamine Receptor | ||
A dopamine D1 receptor antagonist | |||||
| GC61889 | OPC-14523 hydrochloride | 145969-31-9 | Sigma Receptor | ||
OPC-14523 hydrochloride 是一种具有口服活性的 sigma 和 5-HT1A 受体激动剂，对 sigma 受体 (σ1/2 IC50=47/56 nM)、5-HT1A 受体 (IC50=2.3 nM) 和 5-HT 转运体 (IC50=80 nM) 具有高度亲和力。OPC-14523 hydrochloride 显示抗抑郁药样活性。 | |||||
| GC10051 | MDL 100907 | 139290-65-6 | 5-HT Receptor | ||
Selective antagonist of the serotonin receptor 5-HT2A | |||||
| GC17722 | (R)-3,4-DCPG | 201730-10-1 | GluR | ||
AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors | |||||
| GC31690 | Batefenterol (GSK961081) | 743461-65-6 | mAChR | ||
A muscarinic receptor antagonist and β2-adrenergic receptor agonist | |||||
| GC14043 | Nicotine | 22083-74-5 | Neuroscience | ||
An agonist at neuronal nicotinic acetylcholine receptors | |||||
| GC30974 | Promazine hydrochloride | 53-60-1 | Dopamine Receptor | ||
Promazine (Romtiazin, Sinophenin) is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors with antipsychotic effects. | |||||
| GC60072 | Betahistine | 5638-76-6 | Histamine Receptor | ||
A histamine H3 receptor antagonist and histamine H1 receptor agonist | |||||
| GC16787 | Pheniramine Maleate | 132-20-7 | Histamine Receptor | ||
Histamine receptor antagonist | |||||
| GC13995 | Carcinine ditrifluoroacetate | 56897-53-1 | Histamine Receptor | ||
H3 receptor antagonist | |||||
| GC16302 | RuBi-Nicotine | 1256362-30-7 | Nicotinic Receptor | ||
Nicotinic receptor agonist | |||||
| GC17075 | NPEC-caged-dopamine | 1257326-23-0 | Dopamine Receptor | ||
Dopamine receptor agonist | |||||