关于 "NF-κB" 的结果41 个结果
- PTD-p65-P1 Peptide
PTD-p65-P1 Peptide 是一种核转录因子 NF-kappaB 抑制剂，由一个 antennapedia 衍生的膜转运肽序列 (PTD) 连接 p65-P1 构成, 选择性地抑制由各种刺激诱导的 NF-kappaB 活性。
NF-κB - 2,5-DihydroxyacetophenoneCAS: 490-78-8
2',5'-Dihydroxyacetophenone (DHAP, 2-Acetylhydroquinone, Quinacetophenone) is a mixture of dihydroxyacetophenone isomers is used in food flavouring. 2',5'-Dihydroxyacetophenone significantly inhibits NO production via the suppression of iNOS expression. 2',5'-Dihydroxyacetophenone significantly decreases levels of the pro-inflammatory cytokines TNF-α and IL-6 by blocking the ERK1/2 and NF-κB signaling pathways.
NF-κB - PTD-p65-P1 Peptide TFA
PTD-p65-P1 Peptide TFA 是一种核转录因子 NF-kappaB 抑制剂，由一个 antennapedia 衍生的膜转运肽序列 (PTD) 连接 p65-P1 构成, 选择性地抑制由各种刺激诱导的 NF-kappaB 活性。
- Ethyl CaffeateCAS: 102-37-4
Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro.
- Isoliquiritin apiosideCAS: 120926-46-7
Isoliquiritin apioside (ISLA, ILA), a component isolated from Glycyrrhizae radix rhizome (GR), significantly decreases PMA-induced increases in matrix metalloproteinase (MMP) activities and suppresses PMA-induced activation of mitogen-activated protein kinase (MAPK) and NF-κB. Isoliquiritin apioside possesses anti-metastatic and anti-angiogenic abilities in malignant cancer cells and ECs, with no cytotoxicity.
- (E/Z)-IT-603CAS: 292168-90-2
(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603. IT-603 is a NF-κB family member c-Rel inhibitor with an IC50 of 3 μM in electrophoretic mobility shift assay (EMSA).
NF-κB - GalloylpaeoniflorinCAS: 122965-41-7
Galloylpaeoniflorin 是 NF-κB 抑制剂。并且 Galloylpaeoniflorin 是一种DNA裂解的抑制剂。
NF-κB - TNFα activity modulator 3CAS: 2248726-53-4
TNFα activity modulator 3（例6）是TNF活性调节剂，可抑制TNFα诱导的NF-κB活化，可用于相关研究。
NF-κB
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC37036 | PTD-p65-P1 Peptide | - | NF-κB | ||
PTD-p65-P1 Peptide 是一种核转录因子 NF-kappaB 抑制剂，由一个 antennapedia 衍生的膜转运肽序列 (PTD) 连接 p65-P1 构成, 选择性地抑制由各种刺激诱导的 NF-kappaB 活性。 | |||||
| GC39325 | 2,5-Dihydroxyacetophenone | 490-78-8 | NF-κB | ||
2',5'-Dihydroxyacetophenone (DHAP, 2-Acetylhydroquinone, Quinacetophenone) is a mixture of dihydroxyacetophenone isomers is used in food flavouring. 2',5'-Dihydroxyacetophenone significantly inhibits NO production via the suppression of iNOS expression. 2',5'-Dihydroxyacetophenone significantly decreases levels of the pro-inflammatory cytokines TNF-α and IL-6 by blocking the ERK1/2 and NF-κB signaling pathways. | |||||
| GC38520 | PTD-p65-P1 Peptide TFA | - | Peptides | ||
PTD-p65-P1 Peptide TFA 是一种核转录因子 NF-kappaB 抑制剂，由一个 antennapedia 衍生的膜转运肽序列 (PTD) 连接 p65-P1 构成, 选择性地抑制由各种刺激诱导的 NF-kappaB 活性。 | |||||
| GC38678 | Ethyl Caffeate | 102-37-4 | PGE synthase | ||
Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro. | |||||
| GC39095 | Isoliquiritin apioside | 120926-46-7 | p38 | ||
Isoliquiritin apioside (ISLA, ILA), a component isolated from Glycyrrhizae radix rhizome (GR), significantly decreases PMA-induced increases in matrix metalloproteinase (MMP) activities and suppresses PMA-induced activation of mitogen-activated protein kinase (MAPK) and NF-κB. Isoliquiritin apioside possesses anti-metastatic and anti-angiogenic abilities in malignant cancer cells and ECs, with no cytotoxicity. | |||||
| GC50139 | SP 100030 | 154563-54-9 | NF-κB | ||
SP 100030 是一种有效的 NF-κB 和 activator protein-1 (AP-1) 双抑制剂（IC50s 分别为 50 和 50 nM）。 | |||||
| GC42880 | Avenanthramide-C methyl ester | 955382-52-2 | Transcription Factors | ||
Inhibitor of NF-κB activation | |||||
| GC43165 | CAY10512 | 139141-12-1 | Antioxidants | ||
A potent inhibitor of NF-κB | |||||
| GC43190 | CAY10682 | 1542066-74-9 | Transcription Factors | ||
A dual inhibitor of p53-Mdm2 interaction and NF-κB signaling | |||||
| GC31642 | SN50 | 213546-53-3 | NF-κB | ||
SN50， NF-κB细胞通透性抑制肽。 | |||||
| GC31733 | NIK SMI1 | 1660114-31-7 | NF-κB | ||
NIK SMI1 is a highly potent and selective NF-κB-inducing kinase (NIK) inhibitor with Ki of 0.23 nM for NIK-catalyzed hydrolysis of ATP to ADP. | |||||
| GC61564 | (E/Z)-IT-603 | 292168-90-2 | NF-κB | ||
(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603. IT-603 is a NF-κB family member c-Rel inhibitor with an IC50 of 3 μM in electrophoretic mobility shift assay (EMSA). | |||||
| GC64663 | Galloylpaeoniflorin | 122965-41-7 | NF-κB | ||
Galloylpaeoniflorin 是 NF-κB 抑制剂。并且 Galloylpaeoniflorin 是一种DNA裂解的抑制剂。 | |||||
| GC52194 | Dimethylamino Parthenolide | 791595-09-0 | Cell Migration & Metastasis | ||
An inhibitor of NF-κB | |||||
| GC72852 | Helenalin acetate | 10180-86-6 | Histone Demethylases | ||
Helenalin acetate是一种天然的NF-κB抑制剂，是一种有效的C/EBPβ抑制剂。 | |||||
| GC73867 | TNFα activity modulator 3 | 2248726-53-4 | NF-κB | ||
TNFα activity modulator 3（例6）是TNF活性调节剂，可抑制TNFα诱导的NF-κB活化，可用于相关研究。 | |||||
| GC74157 | EN450 | 793719-01-4 | E1/E2/E3 Enzyme | ||
EN450是一种针对NF-κB的半胱氨酸反应性共价分子胶降解剂。 | |||||