GLPBio

关于 "NADPH Oxidase" 的结果11 个结果

筛选:NADPH Oxidase×
  • GC71188 structure
    GC71188
    NADPH oxidase-IN-1
    CAS: 2762405-17-2

    NADPH oxidase-IN-1是一种与神经元炎症相关的口服活性NADPH氧化酶（Nox）抑制剂。

    NADPH Oxidase
  • GC32443 structure
    GC32443
    VAS2870
    CAS: 722456-31-7

    A pan-NADPH oxidase inhibitor

    NADPH Oxidase
  • GC38115 structure
    GC38115
    APX-115 free base
    CAS: 1270084-92-8

    Isuzinaxib (APX-115 free base, Ewha-18278 free base) is a potent, orally active inhibitor of pan NADPH oxidase (pan-Nox) with Ki of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 free base (Ewha-18278 free base) significantly suppresses the expression of inflammatory molecules including MCP-1/CCL2, IL-6, and TNFα in the diabetic kidney.

    NADPH Oxidase
  • GC31367 structure
    GC31367
    GLX351322
    CAS: 835598-94-2

    GLX351322是一种NADPH氧化酶4 (NOX4)抑制剂，IC 50 值为5μM。

    NADPH Oxidase
  • GC32681 structure
    GC32681
    GSK2795039
    CAS: 1415925-18-6

    GSK2795039是一种强效NADPH氧化酶2（NOX2）抑制剂，IC 50 值为0.18μM。

    Other Apoptosis
  • GC12291 structure
    GC12291
    ML 171
    CAS: 6631-94-3

    A selective, cell-active Nox1 inhibitor

    NADPH Oxidase
  • GC12323 structure
    GC12323
    ML-090
    CAS: 531-46-4

    A selective NOX1 inhibitor

    NADPH Oxidase
  • GC11882 structure
    GC11882
    GKT137831
    CAS: 1218942-37-0

    GKT137831是一种口服有效的双重NADPH氧化酶1/4（NOX1/NOX4）抑制剂，活性处于亚微摩尔范围，可预防高糖诱导的人主动脉内皮细胞氧化应激，并减轻糖尿病小鼠的动脉粥样硬化进展。

    Ferroptosis
  • GC50281 structure
    GC50281
    NoxA1ds
    CAS: 1435893-78-9

    NoxA1ds 是一种高效和选择性的 Nox1（NADPH 氧化酶异构体 1）抑制剂。

    NADPH Oxidase
  • GC12520 structure
    GC12520
    Diphenyleneiodonium chloride
    CAS: 4673-26-1

    二苯碘铵 (DPI) 氯化物 (DPIC) 作为 NADH/NADPH 氧化酶抑制剂，对 Mtb 和 S. aureus 具有有效的抗菌活性。

    Reactive Oxygen Species
  • GC63986 structure
    GC63986
    VAS 3947
    CAS: 869853-70-3

    VAS 3947 是一种特异的 NADPH 氧化酶 (NOX) 抑制剂，具有强大的抗血小板作用。VAS 3947 通过 UPR 激活，主要由于蛋白质聚集和错误折叠，独立于抗 NOX 活性诱导细胞凋亡 (apoptosis)。

    Apoptosis