关于 "Nucleoside Antimetabolite/Analogue" 的结果46+ 个结果
- Dalfopristin (RP54476)CAS: 112362-50-2
Dalfopristin (RP54476) is a semi-synthetic analogue of ostreogyrcin A. Quinupristin/dalfopristin (Q/D) is a parental streptogramin with a spectrum of activity that includes Gram-positive pathogens, including those resistant to other classes of antimicrobial compounds.
- ElsulfavirineCAS: 868046-19-9
Elsulfavirine (Elpida, VM-1500) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed for the treatment and prevention of HIV-1 infection.
- Rilpivirine HydrochlorideCAS: 700361-47-3
Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
- CensavudineCAS: 634907-30-5
Censavudine (OBP-601; BMS-986001)，一种核苷类似物，是一种核苷逆转录酶 (nucleoside reverse transcriptase) 抑制剂。Censavudine 是一种有效的 HIV 抑制剂，对 HIV-2 和 HIV-1 的 EC50 范围分别为 30-81 nM 和 450-890 nM。
- DexelvucitabineCAS: 134379-77-4
Dexelbucitabine (Reverset; d-d4FC) 是一种胞苷 类似物，一种具有口服活性的核苷逆转录酶 (nucleoside reverse transcriptase) 抑制剂。Dexelbucitabine 是一种有效的抗 HIV-1 病毒剂，这些病毒聚合酶中含有胸苷类似物和/或 M184V 突变。Dexelvucitabine 是一种 2'-脱氧胞苷抗逆转录病毒剂。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC14452 | Dapivirine (TMC120) | 244767-67-7 | Reverse Transcriptase | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC15452 | Delavirdine mesylate | 147221-93-0 | HIV | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC12301 | Mizoribine | 50924-49-7 | SARS-CoV | ||
An imidazole nucleoside with immunosuppressive properties | |||||
| GC35835 | Delavirdine | 136817-59-9 | Reverse Transcriptase | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC16887 | Tegobuvir | 1000787-75-6 | HCV | ||
A non-nucleoside inhibitor of HCV NS5B | |||||
| GC49823 | 2′-C-β-Methylguanosine | 374750-30-8 | Immunology/Inflammation | ||
An active nucleoside metabolite of BMS-986094 | |||||
| GC46533 | 2-Amino-6-chloropurine | 10310-21-1 | Epstein-Barr | ||
A precursor in the synthesis of nucleoside analogs | |||||
| GC10082 | Vidarabine | 5536-17-4 | Nucleoside Antimetabolite/Analogue | ||
An antiviral nucleoside analog | |||||
| GC15330 | Didanosine | 69655-05-6 | HIV | ||
An antiviral nucleoside analog and inhibitor of reverse transcriptase | |||||
| GC11059 | Rilpivirine | 500287-72-9 | Reverse Transcriptase | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC32105 | Dalfopristin (RP54476) | 112362-50-2 | Bacterial | ||
Dalfopristin (RP54476) is a semi-synthetic analogue of ostreogyrcin A. Quinupristin/dalfopristin (Q/D) is a parental streptogramin with a spectrum of activity that includes Gram-positive pathogens, including those resistant to other classes of antimicrobial compounds. | |||||
| GC62295 | Elsulfavirine | 868046-19-9 | HIV | ||
Elsulfavirine (Elpida, VM-1500) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed for the treatment and prevention of HIV-1 infection. | |||||
| GC17430 | 2-Deoxy-D-glucose | 154-17-6 | Other Apoptosis | ||
2-Deoxy-D-glucose (2DG)，是一种葡萄糖类似物，作为竞争性糖酵解抑制剂。 | |||||
| GC25867 | Rilpivirine Hydrochloride | 700361-47-3 | Reverse Transcriptase | ||
Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz. | |||||
| GC14366 | Thioguanine | 154-42-7 | SARS-CoV | ||
Thioguanine是一种抗白血病和免疫抑制剂，对重组USP2和冠状病毒PLpro的IC50值分别为40µM和25µM。 | |||||
| GC64261 | Censavudine | 634907-30-5 | HIV | ||
Censavudine (OBP-601; BMS-986001)，一种核苷类似物，是一种核苷逆转录酶 (nucleoside reverse transcriptase) 抑制剂。Censavudine 是一种有效的 HIV 抑制剂，对 HIV-2 和 HIV-1 的 EC50 范围分别为 30-81 nM 和 450-890 nM。 | |||||
| GC11654 | Enocitabine | 55726-47-1 | CMV | ||
A prodrug form of cytarabine | |||||
| GC10317 | Lamivudine | 134678-17-4 | SARS-CoV | ||
Lamivudine是一种口服核苷类似物，作为核苷类逆转录酶抑制剂，抗乙肝病毒（HBV）活性的EC50值为0.07±0.02μg/ml。 | |||||
| GC16387 | Nevirapine | 129618-40-2 | HIV | ||
An NNRTI | |||||
| GC14466 | Fluorouracil (Adrucil) | 51-21-8 | DNA/RNA Synthesis | ||
氟尿嘧啶 (Adrucil) (5-FU) 是尿嘧啶的类似物，在 C-5 位置用氟原子代替氢 。 | |||||
| GC64590 | Dexelvucitabine | 134379-77-4 | Reverse Transcriptase | ||
Dexelbucitabine (Reverset; d-d4FC) 是一种胞苷 类似物，一种具有口服活性的核苷逆转录酶 (nucleoside reverse transcriptase) 抑制剂。Dexelbucitabine 是一种有效的抗 HIV-1 病毒剂，这些病毒聚合酶中含有胸苷类似物和/或 M184V 突变。Dexelvucitabine 是一种 2'-脱氧胞苷抗逆转录病毒剂。 | |||||
| GC10387 | 3'-Azido-3'-deoxythymidine β-D-glucuronide (sodium salt) | 133525-01-6 | Reverse Transcriptase | ||
A zidovudine metabolite | |||||