关于 "Reverse Transcriptase" 的结果39+ 个结果
- Reverse transcriptase-IN-1CAS: 2380001-43-2
Reverse transcriptase-IN-1 (Compound 12z)，二芳基苯并嘧啶 (DABP) 类似物， 是一种有效的，具有口服活性的 HIV-1 非核苷逆转录酶抑制剂。Reverse transcriptase-IN-1 具有抗病毒活性，对 HIV-1 IIIB，E138K 和 K103N 突变体的 EC50 值分别为 3.4 nM，4.3 nM 和 3.6 nM，而且对 HIV-1 逆转录酶的 IC50 值为 13.7 nM。
- Tenofovir diphosphate (sodium salt)
An HIV reverse transcriptase and HBV polymerase inhibitor
- 2',3'-Dideoxyadenosine 5'-triphosphate (lithium salt)
An inhibitor of reverse transcriptases and DNA polymerases
- ElsulfavirineCAS: 868046-19-9
Elsulfavirine (Elpida, VM-1500) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed for the treatment and prevention of HIV-1 infection.
- Rilpivirine HydrochlorideCAS: 700361-47-3
Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
- Tenofovir alafenamide fumarateCAS: 379270-38-9
Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.
- UlonivirineCAS: 1591823-76-5
Ulonivirine (MK-8507) 是一种具有口服活性的非核苷逆转录酶（reverse transcriptase）抑制剂，具有较高的抗病毒活性。Ulonivirine 可用于 HIV-1 感染的研究。
- (S)-TenofovirCAS: 147127-19-3
(S)-Tenofovir ((S)-GS 1278) 是 Tenofovir 的低活性 S 型异构体。Tenofovir 是一种核苷酸逆转录酶 (nucleotide reverse transcriptase) 抑制剂，可用于治疗 HIV 和慢性乙型肝炎 (Hepatitis B; HBV)。
- CensavudineCAS: 634907-30-5
Censavudine (OBP-601; BMS-986001)，一种核苷类似物，是一种核苷逆转录酶 (nucleoside reverse transcriptase) 抑制剂。Censavudine 是一种有效的 HIV 抑制剂，对 HIV-2 和 HIV-1 的 EC50 范围分别为 30-81 nM 和 450-890 nM。
- DexelvucitabineCAS: 134379-77-4
Dexelbucitabine (Reverset; d-d4FC) 是一种胞苷 类似物，一种具有口服活性的核苷逆转录酶 (nucleoside reverse transcriptase) 抑制剂。Dexelbucitabine 是一种有效的抗 HIV-1 病毒剂，这些病毒聚合酶中含有胸苷类似物和/或 M184V 突变。Dexelvucitabine 是一种 2'-脱氧胞苷抗逆转录病毒剂。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC63523 | Reverse transcriptase-IN-1 | 2380001-43-2 | HIV | ||
Reverse transcriptase-IN-1 (Compound 12z)，二芳基苯并嘧啶 (DABP) 类似物， 是一种有效的，具有口服活性的 HIV-1 非核苷逆转录酶抑制剂。Reverse transcriptase-IN-1 具有抗病毒活性，对 HIV-1 IIIB，E138K 和 K103N 突变体的 EC50 值分别为 3.4 nM，4.3 nM 和 3.6 nM，而且对 HIV-1 逆转录酶的 IC50 值为 13.7 nM。 | |||||
| GC32306 | Islatravir (MK-8591) | 865363-93-5 | Reverse Transcriptase | ||
A nucleoside reverse transcriptase inhibitor | |||||
| GC13653 | Emtricitabine | 143491-57-0 | HIV | ||
A nucleoside reverse transcriptase inhibitor | |||||
| GC14720 | Zalcitabine | 7481-89-2 | HIV | ||
A nucleoside reverse transcriptase inhibitor | |||||
| GC49776 | Apricitabine | 160707-69-7 | HIV | ||
A nucleoside reverse transcriptase inhibitor | |||||
| GC32390 | MIV-150 (PC 815) | 231957-54-3 | HIV | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC19126 | Doravirine | 1338225-97-0 | Reverse Transcriptase | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC14452 | Dapivirine (TMC120) | 244767-67-7 | Reverse Transcriptase | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC15452 | Delavirdine mesylate | 147221-93-0 | HIV | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC35835 | Delavirdine | 136817-59-9 | Reverse Transcriptase | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC37690 | Stavudine sodium | 134624-73-0 | Reverse Transcriptase | ||
An inhibitor of HIV reverse transcriptase | |||||
| GC60357 | Tenofovir diphosphate | 166403-66-3 | Reverse Transcriptase | ||
An HIV reverse transcriptase and HBV polymerase inhibitor | |||||
| GC45012 | Tenofovir diphosphate (sodium salt) | - | Drug Metabolite | ||
An HIV reverse transcriptase and HBV polymerase inhibitor | |||||
| GC52501 | 2',3'-Dideoxyadenosine 5'-triphosphate (lithium salt) | - | HIV | ||
An inhibitor of reverse transcriptases and DNA polymerases | |||||
| GC15330 | Didanosine | 69655-05-6 | HIV | ||
An antiviral nucleoside analog and inhibitor of reverse transcriptase | |||||
| GC11059 | Rilpivirine | 500287-72-9 | Reverse Transcriptase | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC12830 | Stavudine (d4T) | 3056-17-5 | Other Apoptosis | ||
An inhibitor of HIV reverse transcriptase | |||||
| GC62295 | Elsulfavirine | 868046-19-9 | HIV | ||
Elsulfavirine (Elpida, VM-1500) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed for the treatment and prevention of HIV-1 infection. | |||||
| GC25867 | Rilpivirine Hydrochloride | 700361-47-3 | Reverse Transcriptase | ||
Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz. | |||||
| GC37758 | Tenofovir alafenamide fumarate | 379270-38-9 | Reverse Transcriptase | ||
Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection. | |||||
| GC70089 | Ulonivirine | 1591823-76-5 | Reverse Transcriptase | ||
Ulonivirine (MK-8507) 是一种具有口服活性的非核苷逆转录酶（reverse transcriptase）抑制剂，具有较高的抗病毒活性。Ulonivirine 可用于 HIV-1 感染的研究。 | |||||
| GC39317 | (S)-Tenofovir | 147127-19-3 | SARS-CoV | ||
(S)-Tenofovir ((S)-GS 1278) 是 Tenofovir 的低活性 S 型异构体。Tenofovir 是一种核苷酸逆转录酶 (nucleotide reverse transcriptase) 抑制剂，可用于治疗 HIV 和慢性乙型肝炎 (Hepatitis B; HBV)。 | |||||
| GC64261 | Censavudine | 634907-30-5 | HIV | ||
Censavudine (OBP-601; BMS-986001)，一种核苷类似物，是一种核苷逆转录酶 (nucleoside reverse transcriptase) 抑制剂。Censavudine 是一种有效的 HIV 抑制剂，对 HIV-2 和 HIV-1 的 EC50 范围分别为 30-81 nM 和 450-890 nM。 | |||||
| GC64590 | Dexelvucitabine | 134379-77-4 | Reverse Transcriptase | ||
Dexelbucitabine (Reverset; d-d4FC) 是一种胞苷 类似物，一种具有口服活性的核苷逆转录酶 (nucleoside reverse transcriptase) 抑制剂。Dexelbucitabine 是一种有效的抗 HIV-1 病毒剂，这些病毒聚合酶中含有胸苷类似物和/或 M184V 突变。Dexelvucitabine 是一种 2'-脱氧胞苷抗逆转录病毒剂。 | |||||