关于 "FAS" 的结果18 个结果
- FasnallCAS: 929978-58-5
Fasnall, a thiophenopyrimidine, is a selective fatty acid synthase (FASN) inhibitor that shows potent anti-tumor activity.
- CB2R/FAAH modulator-3CAS: 2876918-67-9
CB2R/FAAH modulator-3 (compound 27) 是一种双重靶向调节剂，可以作为 CB2R 激动剂和 FAAH 抑制剂。CB2R/FAAH modulator-3 作用于 CB2R 和 CB1R 的 Ki 值分别是 20.1 和 67.6 nM，作用于 FAAH 的IC50值为 3.4 μM。CB2R/FAAH modulator-3 可用于癌症、神经退行性疾病中发生的有害炎症级联反应以及 COVID-19 感染相关研究。
- FASN-IN-4 tosylateCAS: 2095432-57-6
FASN-IN-4tosylate是高效的脂肪酸合酶FASN抑制剂，来自专利WO2012064642A1化合物实例29，IC50值为10nM。
- FASN-IN-5CAS: 1309805-49-9
FASN-IN-5 (example 11) 是 FASN 抑制剂，可用于研究 TH17 或 CSF1 介导的疾病或障碍，例如癌症、免疫障碍和肥胖症。
- CB2R/FAAH modulator-2CAS: 2876918-68-0
CB2R/FAAH modulator-2 (compound 26) 是一种双重靶向调节剂，可以作为 CB2R 激动剂和 FAAH 抑制剂。CB2R/FAAH modulator-2 作用于 CB2R 和 CB1R 的 Ki 值分别是 10.8 和 152.9 nM，作用于FAAH 的 IC50 值为 6.2 μM。CB2R/FAAH modulator-2 可用于癌症、神经退行性疾病中发生的有害炎症级联反应以及 COVID-19 感染相关研究。
- Dual FAAH/sEH-IN-1CAS: 2756099-59-7
Dual FAAH/sEH-IN-1(化合物3)是一种高亲和力的双可溶性环氧化物水解酶(sEH)和脂肪酸酰胺水解酶(FAAH)抑制剂，IC50值分别为9.6 nM和7 nM。
- trans,trans-Farnesyl pyrophosphate ammonium saltCAS: 116057-57-9
An intermediate in sterol biosynthesis
- Ammonium iron(III) citrateCAS: 1185-57-5
Ammonium ferric citrate (Ferric ammonium citrate, Ammonium iron(III) citrate, Iron ammonium citrate, FerriSeltz) induces ferroptosis in non-small-cell lung carcinoma through the inhibition of GPX4-GSS/GSR-GGT axis activity.
- NFAT Inhibitor (cell-permeable) (trifluoroacetate salt)
A cell-permeable form of NFAT inhibitor
- FT113CAS: 1630808-89-7
FT113 is a potent inhibitor of fatty acid synthase (FAS/FASN) with ic50 of 213 nM.
- trans-ChalconeCAS: 614-47-1
Trans-Chalcone, the backbone of flavonoids, also is a potent fatty acid synthase (FAS) with IC50 of 17.1 μg/mL, and α-amylase inhibitor, causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7, exerting antifungal and anticancer activities.
- (Rac)-IndoximodCAS: 26988-72-7
(Rac)-Indoximod(1-Methyl-DL-tryptophan)是吲哚胺-2,3-双加氧酶(IDO)抑制剂。(Rac)-Indoximod和IFN-γ联用显著降低了表达α-SMA的人心肌成纤维细胞活性，并通过上调IRF-1，Fas和FasL基因诱导凋亡(apoptosis)。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC25411 | Fasnall | 929978-58-5 | Fatty Acid Synthase (FASN) | ||
Fasnall, a thiophenopyrimidine, is a selective fatty acid synthase (FASN) inhibitor that shows potent anti-tumor activity. | |||||
| GC17780 | FTase Inhibitor II | 156707-43-6 | Transferase | ||
Ftase inhibitor | |||||
| GC36023 | FAAH inhibitor 1 | 326866-17-5 | Autophagy | ||
FAAH inhibitor 1是一种选择性的、可逆的脂肪酸酰胺水解酶（FAAH）抑制剂，IC50值为18±8nM。 | |||||
| GC30366 | FAAH-IN-2 | 184475-71-6 | Autophagy | ||
FAAH-IN-2是摘自专利WO/2008/100977A2中的FAAH抑制剂。 | |||||
| GC30751 | FAAH-IN-1 | 1242441-47-9 | Autophagy | ||
FAAH-IN-1是脂肪酸酰胺水解酶(FAAH)抑制剂，对大鼠和人FAAH的IC50值分别为145nM和650nM。 | |||||
| GC68838 | CB2R/FAAH modulator-3 | 2876918-67-9 | FAAH | ||
CB2R/FAAH modulator-3 (compound 27) 是一种双重靶向调节剂，可以作为 CB2R 激动剂和 FAAH 抑制剂。CB2R/FAAH modulator-3 作用于 CB2R 和 CB1R 的 Ki 值分别是 20.1 和 67.6 nM，作用于 FAAH 的IC50值为 3.4 μM。CB2R/FAAH modulator-3 可用于癌症、神经退行性疾病中发生的有害炎症级联反应以及 COVID-19 感染相关研究。 | |||||
| GC60832 | FASN-IN-4 tosylate | 2095432-57-6 | Fatty Acid Synthase (FASN) | ||
FASN-IN-4tosylate是高效的脂肪酸合酶FASN抑制剂，来自专利WO2012064642A1化合物实例29，IC50值为10nM。 | |||||
| GC67894 | FASN-IN-5 | 1309805-49-9 | Fatty Acid Synthase (FASN) | ||
FASN-IN-5 (example 11) 是 FASN 抑制剂，可用于研究 TH17 或 CSF1 介导的疾病或障碍，例如癌症、免疫障碍和肥胖症。 | |||||
| GC68837 | CB2R/FAAH modulator-2 | 2876918-68-0 | FAAH | ||
CB2R/FAAH modulator-2 (compound 26) 是一种双重靶向调节剂，可以作为 CB2R 激动剂和 FAAH 抑制剂。CB2R/FAAH modulator-2 作用于 CB2R 和 CB1R 的 Ki 值分别是 10.8 和 152.9 nM，作用于FAAH 的 IC50 值为 6.2 μM。CB2R/FAAH modulator-2 可用于癌症、神经退行性疾病中发生的有害炎症级联反应以及 COVID-19 感染相关研究。 | |||||
| GC70904 | Dual FAAH/sEH-IN-1 | 2756099-59-7 | FAAH | ||
Dual FAAH/sEH-IN-1(化合物3)是一种高亲和力的双可溶性环氧化物水解酶(sEH)和脂肪酸酰胺水解酶(FAAH)抑制剂，IC50值分别为9.6 nM和7 nM。 | |||||
| GC48782 | 10,13-epoxy-11-methyl-Octadecadienoic Acid | 57818-39-0 | Antioxidants | ||
A furan fatty acid | |||||
| GC15951 | URB597 | 546141-08-6 | Mitophagy | ||
An inhibitor of FAAH | |||||
| GC43653 | trans,trans-Farnesyl pyrophosphate ammonium salt | 116057-57-9 | PPAR | ||
An intermediate in sterol biosynthesis | |||||
| GC61895 | Ammonium iron(III) citrate | 1185-57-5 | Ferroptosis | ||
Ammonium ferric citrate (Ferric ammonium citrate, Ammonium iron(III) citrate, Iron ammonium citrate, FerriSeltz) induces ferroptosis in non-small-cell lung carcinoma through the inhibition of GPX4-GSS/GSR-GGT axis activity. | |||||
| GC52384 | NFAT Inhibitor (cell-permeable) (trifluoroacetate salt) | - | Bone Growth & Remodeling | ||
A cell-permeable form of NFAT inhibitor | |||||
| GC64974 | FT113 | 1630808-89-7 | Fatty Acid Synthase (FASN) | ||
FT113 is a potent inhibitor of fatty acid synthase (FAS/FASN) with ic50 of 213 nM. | |||||
| GC61896 | trans-Chalcone | 614-47-1 | Fatty Acid Synthase (FASN) | ||
Trans-Chalcone, the backbone of flavonoids, also is a potent fatty acid synthase (FAS) with IC50 of 17.1 μg/mL, and α-amylase inhibitor, causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7, exerting antifungal and anticancer activities. | |||||
| GC61750 | (Rac)-Indoximod | 26988-72-7 | IDO | ||
(Rac)-Indoximod(1-Methyl-DL-tryptophan)是吲哚胺-2,3-双加氧酶(IDO)抑制剂。(Rac)-Indoximod和IFN-γ联用显著降低了表达α-SMA的人心肌成纤维细胞活性，并通过上调IRF-1，Fas和FasL基因诱导凋亡(apoptosis)。 | |||||