关于 "Nuclear Receptors" 的结果20+ 个结果
- EP4 Receptor Antagonist 1CAS: 2287259-07-6
EP4 receptor antagonist 1前列腺素E2受体EP4亚型的高效选择性拮抗剂，对人和小鼠EP4受体的半抑制浓度（IC₅₀）分别为6.1nM和16.2nM。
Immunology/Inflammation - Glucocorticoid receptor modulator 1CAS: 2868357-11-1
Glucocorticoid receptor modulator 1是一种口服活性非甾体选择性糖皮质激素受体调节剂，对NF-κB和AP-1的IC50值分别为9 nM和130 nM。
- IFN-α Receptor Recognition Peptide 1CAS: 153840-64-3
IFN-α Receptor Recognition Peptide 1 是 IFN-α 的一个多肽序列，为 IFN-α 受体识别肽。
- NFAT Inhibitor (cell-permeable) (trifluoroacetate salt)
A cell-permeable form of NFAT inhibitor
- (Ala1)-PAR4 (1-6) amide (mouse) (trifluoroacetate salt)
A peptide agonist of PAR4
Immunology/Inflammation - NF-κB Inhibitor (trifluoroacetate salt)
A cell-permeable peptide that blocks nuclear import of NF-κB
- Tapinarof (WBI 1001)CAS: 79338-84-4
Tapinarof (GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505) is a natural agonist of aryl hydrocarbon receptor (AhR) and induces nuclear translocation of AhR in immortalized keratinocytes (HaCaT) with EC50 of 0.16 nM. Tapinarof induces cellular apoptosis in CD4+ T cells in a dosedependent manner with IC50 of 5.2 μM.
- Nrf2-IN-1CAS: 1610022-76-8
Nrf2-IN-1是nuclear factor-erythroid 2-related factor 2 (Nrf2)的抑制剂，用于急性髓系白血病(AML)的研究。
- NylidrinCAS: 447-41-6
An agonist of β-ARs and antagonist of NR1A/2B subunit-containing NMDA receptors
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC32019 | Interferon receptor agonist | 2215120-36-6 | IFNAR | ||
干扰素受体激动剂（化合物 6）是一种干扰素 (IFN) 受体诱导剂。 | |||||
| GC39554 | AT2 receptor agonist C21 | 477775-14-7 | Cardiomyopathy | ||
An AT2 receptor agonist | |||||
| GC17996 | Toll-like receptor modulator | 926927-42-6 | TLR | ||
Toll 样受体调节剂是调节免疫功能的 TLR7/8 调节剂。 | |||||
| GC47297 | EP4 Receptor Antagonist 1 | 2287259-07-6 | Immunology/Inflammation | ||
EP4 receptor antagonist 1前列腺素E2受体EP4亚型的高效选择性拮抗剂，对人和小鼠EP4受体的半抑制浓度（IC₅₀）分别为6.1nM和16.2nM。 | |||||
| GC71181 | Glucocorticoid receptor modulator 1 | 2868357-11-1 | AP-1 | ||
Glucocorticoid receptor modulator 1是一种口服活性非甾体选择性糖皮质激素受体调节剂，对NF-κB和AP-1的IC50值分别为9 nM和130 nM。 | |||||
| GC45063 | Toll-Like Receptor 7 Ligand II | 226907-52-4 | Hepatitis | ||
A TLR7 agonist | |||||
| GC36296 | IFN-α Receptor Recognition Peptide 1 | 153840-64-3 | Peptides | ||
IFN-α Receptor Recognition Peptide 1 是 IFN-α 的一个多肽序列，为 IFN-α 受体识别肽。 | |||||
| GC52384 | NFAT Inhibitor (cell-permeable) (trifluoroacetate salt) | - | Bone Growth & Remodeling | ||
A cell-permeable form of NFAT inhibitor | |||||
| GC40159 | PAR1 (1-6) (mouse, rat) (trifluoroacetate salt) | - | Innate Immunity | ||
A peptide agonist of PAR1 | |||||
| GC52436 | TRAP-6 amide (trifluoroacetate salt) | - | Immunology/Inflammation | ||
A peptide PAR1 agonist | |||||
| GC41697 | (Ala1)-PAR4 (1-6) amide (mouse) (trifluoroacetate salt) | - | Immunology/Inflammation | ||
A peptide agonist of PAR4 | |||||
| GC19254 | ML385 | 846557-71-9 | Ferroptosis | ||
ML385是一种特定的核因子红细胞2相关因子2（NRF2）抑制剂。 | |||||
| GC48985 | NF-κB Inhibitor (trifluoroacetate salt) | - | Innate Immunity | ||
A cell-permeable peptide that blocks nuclear import of NF-κB | |||||
| GC31732 | Tapinarof (WBI 1001) | 79338-84-4 | Aryl Hydrocarbon Receptor | ||
Tapinarof (GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505) is a natural agonist of aryl hydrocarbon receptor (AhR) and induces nuclear translocation of AhR in immortalized keratinocytes (HaCaT) with EC50 of 0.16 nM. Tapinarof induces cellular apoptosis in CD4+ T cells in a dosedependent manner with IC50 of 5.2 μM. | |||||
| GC45567 | SR 1903 | 1414248-06-8 | ROR/RAR/RXR | ||
A modulator of RORγ and LXR receptors | |||||
| GC33306 | IMD-0560 | 439144-66-8 | IκB/IKK | ||
IMD-0560 is an Inhibitor of nuclear factor kappa-B kinase (IKK) which can suppress the production of inflammatory cytokines and chemokines. | |||||
| GC16590 | Dimethyl Fumarate | 624-49-7 | KEAP1-Nrf2 | ||
An antioxidant with immunological actions | |||||
| GC36773 | Nrf2-IN-1 | 1610022-76-8 | KEAP1-Nrf2 | ||
Nrf2-IN-1是nuclear factor-erythroid 2-related factor 2 (Nrf2)的抑制剂，用于急性髓系白血病(AML)的研究。 | |||||
| GC48801 | Nylidrin | 447-41-6 | Neuroscience | ||
An agonist of β-ARs and antagonist of NR1A/2B subunit-containing NMDA receptors | |||||
| GC48202 | Treprostinil (diethanolamine salt) | 830354-48-8 | Transcription Factors | ||
An agonist of IP2, DP2, and EP2 receptors | |||||