关于 "NF-κB" 的结果49+ 个结果

Licoricidin (LCD) 从甘草 Glycyrrhiza uralensis Fisch 中分离，具有抗癌活性。Licoricidin (LCD) 通过诱导周期停滞，诱导细胞凋亡 (apoptosis) 和自噬 (autophagy)，是一种对抗结直肠癌的潜在化学预防或化学治疗剂。Licoricidin (LCD) 通过抑制肿瘤血管生成和淋巴管生成以及肿瘤组织局部微环境的变化抑制肺转移。Licoricidin (LCD) 通过体外和体内 Akt 和 NF-κB 途径的失活，增强吉西他滨诱导的骨肉瘤 (OS) 细胞的细胞毒性。Licoricidin (LCD) 通过 ROS 清除阻断 UVA 诱导的光老化，限制 MMP-1 的活性，被认为是新的局部应用的抗衰老制剂中的活性成分。

Okanin 是 Coreopsis tinctoria 的有效成分。Okanin 通过抑制 TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。

PTD-p65-P1 Peptide 是一种核转录因子 NF-kappaB 抑制剂，由一个 antennapedia 衍生的膜转运肽序列 (PTD) 连接 p65-P1 构成, 选择性地抑制由各种刺激诱导的 NF-kappaB 活性。

2',5'-Dihydroxyacetophenone (DHAP, 2-Acetylhydroquinone, Quinacetophenone) is a mixture of dihydroxyacetophenone isomers is used in food flavouring. 2',5'-Dihydroxyacetophenone significantly inhibits NO production via the suppression of iNOS expression. 2',5'-Dihydroxyacetophenone significantly decreases levels of the pro-inflammatory cytokines TNF-α and IL-6 by blocking the ERK1/2 and NF-κB signaling pathways.

An inhibitor of the NF-κB subunit c-Rel

PTD-p65-P1 Peptide TFA 是一种核转录因子 NF-kappaB 抑制剂，由一个 antennapedia 衍生的膜转运肽序列 (PTD) 连接 p65-P1 构成, 选择性地抑制由各种刺激诱导的 NF-kappaB 活性。

Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro.

Isoliquiritin apioside (ISLA, ILA), a component isolated from Glycyrrhizae radix rhizome (GR), significantly decreases PMA-induced increases in matrix metalloproteinase (MMP) activities and suppresses PMA-induced activation of mitogen-activated protein kinase (MAPK) and NF-κB. Isoliquiritin apioside possesses anti-metastatic and anti-angiogenic abilities in malignant cancer cells and ECs, with no cytotoxicity.

CU-T12-9是一种特异性Toll样受体TLR1/TLR2异二聚体的小分子激动剂，其EC 50 为52.9nM，CU-T12-9通过促进TLR1和TLR2二聚化，进而激活NF-κB信号通路

SP 100030 是一种有效的 NF-κB 和 activator protein-1 (AP-1) 双抑制剂（IC50s 分别为 50 和 50 nM）。

Inhibitor of NF-κB activation

A potent inhibitor of NF-κB

A dual modulator of p53-MDM2 interaction and NF-κB signaling

A dual inhibitor of p53-Mdm2 interaction and NF-κB signaling

A negative control peptide used with NF-κB inhibitor

SN50， NF-κB细胞通透性抑制肽。

NIK SMI1 is a highly potent and selective NF-κB-inducing kinase (NIK) inhibitor with Ki of 0.23 nM for NIK-catalyzed hydrolysis of ATP to ADP.

(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603. IT-603 is a NF-κB family member c-Rel inhibitor with an IC50 of 3 μM in electrophoretic mobility shift assay (EMSA).

Galloylpaeoniflorin 是 NF-κB 抑制剂。并且 Galloylpaeoniflorin 是一种DNA裂解的抑制剂。

An inhibitor of NF-κB

Glucocorticoid receptor modulator 1是一种口服活性非甾体选择性糖皮质激素受体调节剂，对NF-κB和AP-1的IC50值分别为9 nM和130 nM。

STING-IN-4（化合物1）是一种STING抑制剂，可抑制STING表达，从而减少STING和核因子-κB（NF-κB）信号传导的激活。

Helenalin acetate是一种天然的NF-κB抑制剂，是一种有效的C/EBPβ抑制剂。

TNFα activity modulator 3（例6）是TNF活性调节剂，可抑制TNFα诱导的NF-κB活化，可用于相关研究。