关于 "Glucose Transporters" 的结果6 个结果
- Glucosamine (D-Glucosamine)CAS: 3416-24-8
Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.
Autophagy - Danthron (Dantron)CAS: 117-10-2
Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes.
- JPH203 (KYT-0353)CAS: 1037592-40-7
JPH203 (KYT-0353) 是一种选择性 L 型氨基酸转运蛋白 1 抑制剂，显着抑制 HT-29 YD-38 和白血病细胞的亮氨酸摄取和细胞生长，IC50 值分别为 0.06 μM 和 4.1 μM 。
Autophagy
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC30263 | Glucosamine (D-Glucosamine) | 3416-24-8 | Autophagy | ||
Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites. | |||||
| GC30056 | Danthron (Dantron) | 117-10-2 | Virus Protease | ||
Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes. | |||||
| GC11989 | Nortriptyline (hydrochloride) | 894-71-3 | Other Apoptosis | ||
A tricyclic antidepressant | |||||
| GC15605 | Ezetimibe | 163222-33-1 | Autophagy | ||
Ezetimibe是一种选择性胆固醇吸收抑制剂，对肺癌细胞(A549)和人胚肾细胞(HEK293)的IC50为50µM，对黑色素瘤细胞(A375)的IC50为30µM，作用时间均为48h。 | |||||
| GC16775 | Rotenone | 83-79-4 | Other Apoptosis | ||
Rotenone是一种线粒体电子传递链复合物 I 抑制剂，可通过增强线粒体活性氧的产生来诱导细胞凋亡。 | |||||
| GC32690 | JPH203 (KYT-0353) | 1037592-40-7 | Autophagy | ||
JPH203 (KYT-0353) 是一种选择性 L 型氨基酸转运蛋白 1 抑制剂，显着抑制 HT-29 YD-38 和白血病细胞的亮氨酸摄取和细胞生长，IC50 值分别为 0.06 μM 和 4.1 μM 。 | |||||