S-(5’-Adenosyl)-L-methionine iodide (S-Adenosyl-L-methionine iodide) is an important methyl donor that is found in all living organisms[1].
By donating the methyl group, sues that involves perchloric acid extraction has beenSAM is converted into S-adenosyl-L-homocysteine reported by She et al. Separation of SAM and (SAH)[1].
[1]. W Wang, et al. Reversed-phase high-performance liquid chromatography procedure for the simultaneous determination of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine in mouse liver and the effect of methionine on their concentrations. J Chromatogr B Biomed Sci Appl. 2001 Oct 5;762(1):59-65.