GlpBio

Ryanodine

目录号: GC12607纯度: >98.00%同义词: 利阿诺定

Ryanodine 是一种细胞渗透性的ryanodine 受体调节剂。

Ryanodine
Cas No.: 15662-33-6
规格价格库存数量操作
1mg¥4,092.00现货
1
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产品描述 Description

Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa.

Ryanodine (100-5000 nM, 30-120 mintutes) irreversibly depresses twitch and tetanic tension of both fast and slow muscle in a dose-related manner[1]. At concentrations above 250 nM, ryanodine induces a slowly developing, dose dependent contracture which could not be blocked by 5 mMCo2+[1].

References:
[1]. Meissner G, et al. Ryanodine activation and inhibition of the Ca2+ release channel of sarcoplasmic reticulum. J Biol Chem. 1986 May 15;261(14):6300-6.
[2]. Fryer MW, et al. The action of ryanodine on rat fast and slow intact skeletal muscles. J Physiol. 1989 Jul;414:399-413.

产品文档 Product Documents

Purity:>98.00%Appearance:A jelly

化学性质Chemical Properties

CAS 号
15662-33-6
同义词
利阿诺定
化学名
(3R,4R,4aR,4a1R,6R,6aR,7R,8S,8aR,9R,9aR)-4,4a1,6,7,8a,9a-hexahydroxy-7-isopropyl-3,6a,9-trimethyldodecahydro-6,9-methanobenzo[1,2]pentaleno[1,6-bc]furan-8-yl 1H-pyrrole-2-carboxylate
SMILES
O[C@@]1([C@@]([C@]2(C)C3)([C@H]4OC(C5=CC=CN5)=O)O)[C@]([C@@]4(C(C)C)O)(C)[C@]3(O)O[C@]1([C@@H]6O)[C@]2(CC[C@H]6C)O
分子式
C25H35NO9
分子量
493.55 g/mol
溶解性
<12.34mg/ml in DMSO; <4.94mg/ml in ethanol
保存条件
Desiccate at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol