GlpBio

Rp-8-bromo-Cyclic AMPS (sodium salt)

目录号: GC44852纯度: >98%同义词: 8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer, Rp-8-BrcAMPS, Rp-8-bromocAMPS
COASDSData Sheet
An antagonist of cAMP-dependent PKAs
Rp-8-bromo-Cyclic AMPS (sodium salt)
Cas No.: 925456-59-3
规格价格库存数量操作
1mg¥4,050.00现货
1
500μg¥2,695.00现货
1
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产品描述 Description

Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II from bovine heart.

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
925456-59-3
同义词
8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer, Rp-8-BrcAMPS, Rp-8-bromocAMPS
SMILES
O[C@H]1[C@H](N2C(Br)=NC3=C2N=CN=C3N)O[C@H]4[C@H]1O[P@@](OC4)([S-])=O.[Na+]
分子式
C10H10BrN5O5PS •Na
分子量
446.1 g/mol
溶解性
DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 0.5 mg/ml,PBS (pH 7.2): 10 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol