GlpBio

Rhodblock 6

目录号: GC72976纯度: >98.00%
Rhodblock 6是一种Rho激酶（ROCK）抑制剂，抑制磷酸MRLC（肌球蛋白调节轻链）定位。
Rhodblock 6
Cas No.: 886625-06-5
规格价格库存数量操作
5 mg¥936.00现货
1
10 mg¥1,512.00现货
1
25 mg¥3,168.00现货
1
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文献被引

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    183(7):1867-1883 (2020)
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产品描述 Description

Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits phospho-MRLC (myosin regulatory light chain) localization.

Rhodblock 6 (1-30 μM) inhibits ROCK activity robustly and in a dose-dependent manner. Rhodblock 6 also inhibits its human ortholog, ROCK I, and Rhodblock 6 (100 μM; 20 h) causes the disruption of stress fibers in human HeLa cells[1].

References:
[1]. Adam B Castoreno, et al. Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis. Nat Chem Biol. 2010 Jun;6(6):457-63.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
886625-06-5
分子式
C12H13N3O
分子量
215.25 g/mol
溶解性
DMSO : 125 mg/mL (580.72 mM; Need ultrasonic)
保存条件
4°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol