EZH2
EZH2(zeste 同源物 2增强子)
EZH2 (enhancer of zeste homolog 2) is a polycomb group protein and histone methyltrasferase that associated with transcriptional repression. It catalyzes trimethylation of H3K27me3 (histone H3 lysine 27) as a catalytic subunit of PRC2 (polycomb repressive complex 2).
EZH2 相关产品(10)
- GC131453-Deazaneplanocin,DZNepCAS: 102052-95-9纯度: >98.00%
An inhibitor of lysine methyltransferase EZH2
- GC179073-Deazaneplanocin A (DZNep) hydrochlorideCAS: 120964-45-6纯度: >99.50%
3-Deazaneplanocin A (DZNep) hydrochloride 是一种腺苷类似物，是一种竞争性 S-腺苷高半胱氨酸水解酶抑制剂，在无细胞试验中的 Ki 为 50 pM。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC13145 | 3-Deazaneplanocin,DZNep | 102052-95-9 | >98.00% | |
An inhibitor of lysine methyltransferase EZH2 | ||||
| GC13878 | EPZ005687 | 1396772-26-1 | >99.00% | |
A potent, selective inhibitor of EZH2 | ||||
| GC17907 | 3-Deazaneplanocin A (DZNep) hydrochloride | 120964-45-6 | >99.50% | |
3-Deazaneplanocin A (DZNep) hydrochloride 是一种腺苷类似物，是一种竞争性 S-腺苷高半胱氨酸水解酶抑制剂，在无细胞试验中的 Ki 为 50 pM。 | ||||
| GC11414 | GSK503 | 1346572-63-1 | >99.50% | |
A potent, selective EZH2 inhibitor | ||||
| GC15783 | GSK126 | 1346574-57-9 | >98.00% | |
GSK126(GSK2816126A, GSK2816126)是一种高选择性EZH2甲基转移酶抑制剂，在体外的IC 50 为12.6~17.4nM；在体内的IC 50 为9.9nM。 | ||||
| GC17534 | GSK343 | 1346704-33-3 | >98.00% | |
A selective, cell-permeable EZH2 inhibitor | ||||
| GC14756 | EI1 | 1418308-27-6 | >99.50% | |
A selective inhibitor of EZH2 | ||||
| GC11484 | CPI-169 S-enantiomer | - | - | |
EZH2 inhibitor | ||||
| GC12146 | CPI-169 R-enantiomer | 1802175-07-0 | - | |
EZH2 inhibitor | ||||
| GC16599 | CPI-169 | 1450655-76-1 | >98.00% | |
A selective EZH2 inhibitor | ||||