GlpBio

MDR multidrug resistance

MDR multidrug resistance(多药耐药)

MDR (multidrug resistance) is a property that first identified in tumor cell, hat the resistance of tumor cell is to a variety of chemotherapy agent due to active efflux via transporter proteins.

MDR multidrug resistance 相关产品(43)

  • GC48119 structure
    GC48119Suprafenacine
    CAS: 1477482-50-0
    纯度: >98.00%

    An inhibitor of tubulin polymerization with anticancer activity

  • GC48219 structure
    GC48219Ulipristal Acetate-d6
    CAS: 1621894-64-1
    纯度: >99.00%

    An internal standard for the quantification of ulipristal acetate

  • GC48479 structure
    GC48479Migrastatin
    CAS: 314245-65-3
    纯度: >90.00%

    A fungal metabolite with antimuscarinic and anticancer activities

  • GC49106 structure
    GC49106Gentisein
    CAS: 529-49-7
    纯度: >95.00%

    A xanthone with diverse biological activities

  • GC49251 structure
    GC49251Oxaliplatin-d10
    CAS: 1132819-16-9
    纯度: >99.00%

    An internal standard for the quantification of oxaliplatin

  • GC49275 structure
    GC492758-Oxycoptisine
    CAS: 19716-61-1
    纯度: >98.00%

    An isoquinoline alkaloid with anticancer and gastroprotective activities

  • GC49308 structure
    GC49308Ungeremine
    CAS: 2121-12-2
    纯度: >98.00%

    A betaine-type alkaloid with diverse biological activities

  • GC49670 structure
    GC49670Indium (III) thiosemicarbazone 5b
    CAS: 2345755-20-4
    纯度: >95.00%

    An anticancer agent

  • GC52104 structure
    GC52104Ponatinib (hydrochloride)
    CAS: 1114544-31-8
    纯度: >98.00%

    Ponatinib (hydrochloride)是一种多靶点酪氨酸激酶抑制剂，可抑制Abl（IC 50 =0.37nM），PDGFRα（IC 50 =1.1nM），VEGFR2（IC 50 =1.5nM），FGFR1（IC 50 =2.2nM）和Src（IC 50 =5.4nM）的活性。

  • GC52455 structure
    GC52455Pixantrone-d8 (maleate)
    纯度: >99.00%

    An internal standard for the quantification of pixantrone

  • GC90543 structure
    GC90543EGFR Peptide (human, mouse) (myristoylated) (trifluoroacetate salt)
    纯度: >95.00%

    一种PKC抑制剂

  • GC90660 structure
    GC90660Fz25
    CAS: 2762498-70-2
    纯度: >98.00%

    一种三唑修饰的甾醇和抗癌药物。

  • GC91057 structure
    GC91057HP661
    纯度: >98.00%

    一种线粒体复合物I抑制剂。

  • GC91096 structure
    GC91096S-72
    CAS: 2446799-14-8
    纯度: >98.00%

    一种微管聚合抑制剂。

  • GC91135 structure
    GC911354-(3,4-Difluorobenzo)curcumin
    CAS: 1170354-22-9
    纯度: >95.00%

    一种半合成的香豆素，具有抗寄生虫和抗癌活性。

  • GC91152 structure
    GC91152Flavokawain 1i
    CAS: 1098176-51-2
    纯度: >98.00%

    一种具有抗癌和抗病毒活性的黄樟素衍生物。

  • GC91154 structure
    GC9115433-BCRP Inhibitor
    纯度: >98.00%

    一种BCRP抑制剂

  • GC91403 structure
    GC91403HR68
    CAS: 2454582-64-8
    纯度: >98.00%

    HR68是一种抗癌药物，是过氧化物酶体增殖激活受体（PPAR）激动剂芬布拉酸的衍生物。它可以降低LN-229恶性胶质母细胞瘤细胞的存活率（IC50 = 1.17uM）。

  • GC91435 structure
    GC91435YCH1899
    纯度: >98.00%

    YCH1899是一种聚(ADP-核糖)聚合酶1(PARP1)和PARP2的抑制剂(IC50s = 1)，它选择性地作用于PARP1和PARP2，而不影响PARP3、-4、-5A、-5B、-6、-7、-10和-12 (IC50s = 1 -14.1 nM)。