P450
Cytochrome P450 are a family of heme-containing monoxygenases catalyzing the metabolism of xenobiotics in the body where P450 enzymes use O2 and two electrons provided by NAD(P)H with the help of redox partner flavoproteins and iron-sulfur proteins to catalyze the monooxygenation of a variety of substrates. Based on how electrons from NAD(P)H are delivered to the catalytic site, P450 enzymes are divided into four classes, including Class I requiring both an FAD-containing reductase and an iron sulfur redoxin, Class II requiring only an FAD/FMN-containg P450 reductase, Class III requiring no electron donor and Class IV requiring electrons directly from NAD(P)H.
P450 相关产品(439)
- GC44819Resorufin benzyl etherCAS: 87687-02-3纯度: >98.00%
A fluorometric substrate for CYP450-linked enzymes
- GC44975SW203668 (trifluoroacetate salt)CAS: 2117405-48-6纯度: >98.00%
An irreversible inhibitor of stearoyl-CoA desaturase
- GC45270(±)10(11)-EDP EthanolamideCAS: 2123484-71-7纯度: >98.00%
An ω-3 endocannabinoid epoxide and CB receptor agonist
- GC45582trans-ε-ViniferinCAS: 62218-08-0纯度: >90.00%
A stilbene polyphenol with diverse biological activities
- GC45887Bufuralol-d9 (hydrochloride)CAS: 1173023-51-2纯度: >99.00%
An internal standard for the quantification of bufuralol
- GC45919(±)5(6)-EET-d11 methyl ester纯度: >99.00%
A neuropeptide with diverse biological activities
- GC45920(±)14(15)-EET-d11 methyl ester纯度: >99.00%
A neuropeptide with diverse biological activities
- GC45921(±)8(9)-EET-d11 methyl ester纯度: >99.00%
A neuropeptide with diverse biological activities
- GC45922(±)11(12)-EET-d11 methyl ester纯度: >99.00%
A neuropeptide with diverse biological activities
- GC462417-keto Cholesterol-d7CAS: 127684-08-6纯度: >99.00%
An internal standard for the quantification of 7-keto cholesterol
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC44668 | Posaconazole D-Glucuronide | - | >80.00% | |
A metabolite of posaconazole | ||||
| GC44799 | Quinidine N-oxide | 70116-00-6 | >95.00% | |
A quinidine metabolite | ||||
| GC44819 | Resorufin benzyl ether | 87687-02-3 | >98.00% | |
A fluorometric substrate for CYP450-linked enzymes | ||||
| GC44882 | Seneciphylline | 480-81-9 | >99.50% | |
An alkaloid with diverse biological activities | ||||
| GC44907 | S-NEPC | 147349-28-8 | >98.00% | |
A colorimetric substrate for sEH | ||||
| GC44917 | Sorafenib N-oxide | 583840-03-3 | >98.00% | |
An active metabolite of sorafenib | ||||
| GC44975 | SW203668 (trifluoroacetate salt) | 2117405-48-6 | >98.00% | |
An irreversible inhibitor of stearoyl-CoA desaturase | ||||
| GC45023 | tetranor-12(R)-HETE | 135271-51-1 | >98.00% | |
A metabolite of 12(R)-HETE | ||||
| GC45151 | Voriconazole N-oxide | 618109-05-0 | >95.00% | |
A major metabolite of voriconazole | ||||
| GC45208 | α-hydroxy Metoprolol | 56392-16-6 | >98.00% | |
An active metabolite of metoprolol | ||||
| GC45239 | δ4-Abiraterone | 154229-21-7 | >99.00% | |
An active metabolite of abiraterone | ||||
| GC45269 | (±)10(11)-DiHDPA | 1345275-22-0 | >98.00% | |
An epoxygenase metabolite of DHA | ||||
| GC45270 | (±)10(11)-EDP Ethanolamide | 2123484-71-7 | >98.00% | |
An ω-3 endocannabinoid epoxide and CB receptor agonist | ||||
| GC45271 | (±)11(12)-EET Ethanolamide | - | >98.00% | |
A potential cytochrome P450 metabolite of AEA | ||||
| GC45508 | MEGX (hydrochloride) | 7729-94-4 | >95.00% | |
An active metabolite of lidocaine | ||||
| GC45582 | trans-ε-Viniferin | 62218-08-0 | >90.00% | |
A stilbene polyphenol with diverse biological activities | ||||
| GC45650 | Des(benzylpyridyl) Atazanavir | 1192224-24-0 | >98.00% | |
A metabolite of atazanavir | ||||
| GC45887 | Bufuralol-d9 (hydrochloride) | 1173023-51-2 | >99.00% | |
An internal standard for the quantification of bufuralol | ||||
| GC45919 | (±)5(6)-EET-d11 methyl ester | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45920 | (±)14(15)-EET-d11 methyl ester | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45921 | (±)8(9)-EET-d11 methyl ester | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45922 | (±)11(12)-EET-d11 methyl ester | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45969 | 6β-hydroxy Eplerenone | 209253-80-5 | >95.00% | |
A major metabolite of eplerenone | ||||
| GC46241 | 7-keto Cholesterol-d7 | 127684-08-6 | >99.00% | |
An internal standard for the quantification of 7-keto cholesterol | ||||