PKD

PKD(蛋白激酶D)

Protein kinase D (PKD) are a family of serine/threonine kinases comprised of three different but closely related members of Calmodulin-dependent protein kinases, including PKD1, PKD2 and PKD3, that are involved in fission of vesicles at the Golgi compartment, coordination of cell migration and invasion, and regulation of gene transcription. All PKD protein kinases are diacylglycerol (DAG) receptors characterized by the presence of a highly conserved N-terminal regulatory domain, which consists of two zinc finger-like cysteine-rich domains, and an autoinhibitory pleckstrin homology (PH) domain. DAG is able to bind to the cysteine-rich domain of PKD enzymes, which is crucial for kinase activation.

PKD 相关产品(7)

GC11319 kb NB 142-70
CAS: 1233533-04-4
纯度: >98.00%
A selective PKD inhibitor
GC13589 CID 755673
CAS: 521937-07-5
纯度: >99.50%
An inhibitor of protein kinase D
GC15718 CID 2011756
CAS: 638156-11-3
An inhibitor of protein kinase D
GC14355 CRT5
CAS: 1034297-58-9
A pan PKD inhibitor
GC35750 CRT0066101 dihydrochloride
CAS: 1883545-60-5
纯度: >98.00%
CRT0066101 dihydrochloride is a small molecule PKD family specific inhibitor which specifically blocks PKD1/2 activity and does not suppress PKCα/PKCβ/PKCε activity in multiple.
GC43326 CRT0066101 (hydrochloride)
CAS: 1290629-45-6
纯度: >95.00%
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling.
GC68537 3-IN-PP1
CAS: 2227110-54-3
3-IN-PP1 是一种蛋白激酶 D (PKD) 抑制剂。 3-IN-PP1 对 PKD1、PKD2 和 PKD3 具有有效广泛的 PKD 抑制活性， IC50 值分别为 108、94 和 108 nM。3-IN-PP1 也是一种广谱抗癌剂，对多种肿瘤细胞的生长有抑制作用。3-IN-PP1 可用于癌症研究。

分类产品列表
货号	产品名称	CAS号	纯度
GC11319	kb NB 142-70	1233533-04-4	>98.00%
GC11319	A selective PKD inhibitor
GC13589	CID 755673	521937-07-5	>99.50%
GC13589	An inhibitor of protein kinase D
GC15718	CID 2011756	638156-11-3	-
GC15718	An inhibitor of protein kinase D
GC14355	CRT5	1034297-58-9	-
GC14355	A pan PKD inhibitor
GC35750	CRT0066101 dihydrochloride	1883545-60-5	>98.00%
GC35750	CRT0066101 dihydrochloride is a small molecule PKD family specific inhibitor which specifically blocks PKD1/2 activity and does not suppress PKCα/PKCβ/PKCε activity in multiple.
GC43326	CRT0066101 (hydrochloride)	1290629-45-6	>95.00%
GC43326	Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling.
GC68537	3-IN-PP1	2227110-54-3	-
GC68537	3-IN-PP1 是一种蛋白激酶 D (PKD) 抑制剂。 3-IN-PP1 对 PKD1、PKD2 和 PKD3 具有有效广泛的 PKD 抑制活性， IC50 值分别为 108、94 和 108 nM。3-IN-PP1 也是一种广谱抗癌剂，对多种肿瘤细胞的生长有抑制作用。3-IN-PP1 可用于癌症研究。