GlpBio

PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt)

目录号: GC92090纯度: >99.00%同义词: DPPI-4,5-P<sub>2</sub>-d<sub>62</sub>; Phosphatidy<wbr>linositol-4,5-<wbr>diphosphate C<sub>16</sub>-d<sub>62</sub>; PI(4,5)P<sub>2</sub> (16:0/16:0)-d<sub>62</sub>; PIP2[4',5'](16:0/16:0)-d<sub>62</sub>
PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt)旨在用作通过GC或LC质谱定量PtdIns-4,5-P2 1,2-二棕榈酰钠盐的内标。
PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt)
规格价格库存数量操作
25 &#181;g¥1,302.00现货
1
50 &#181;g¥2,464.00现货
1
100 &#181;g¥4,620.00现货
1
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产品描述 Description

PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt) is intended for use as an internal standard for the quantification of PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt) by GC- or LC-mass spectrometry. The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 PtdIns-4,5-P2-(1,2-dipalmitoyl)-d62 is a synthetic analog of natural PtdIns containing deuterated C16:0 fatty acids at the sn-1 and sn-2 positions. This synthetic standard features the same inositol and diacyl glycerol (DAG) stereochemistry as that of the natural compound. The natural compound is the product of phosphatidylinositol 4-phosphate 5-kinase acting on PtdIns-(4)-P1. Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.

References:
[1]. Exton, J.H.Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteinsAnnu. Rev. Pharmacol. Toxicol.36481-509(1996).
[2]. Majerus, P.W.Inositol phosphate biochemistryAnnu. Rev. Biochem.61225-250(1992).

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

同义词
DPPI-4,5-P<sub>2</sub>-d<sub>62</sub>; Phosphatidy<wbr>linositol-4,5-<wbr>diphosphate C<sub>16</sub>-d<sub>62</sub>; PI(4,5)P<sub>2</sub> (16:0/16:0)-d<sub>62</sub>; PIP2[4',5'](16:0/16:0)-d<sub>62</sub>
化学名
1-(1,2-dihexadecanoyl(2,2’,3,3’,4,4’,5,5’,6,6’,7,7’,8,8’,9,9’,10,10’,11,11’,12,12’,13,13’,14,14’,15,16,16,16-d31)phosphatidyl)inositol-4,5-bisphosphate, trisodium salt
SMILES
O[C@@H]1[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@@H](O)[C@H]1OP([O-])(OCC(COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)=O.[Na+].[Na+].[Na+]
分子式
C41H16D62O19P3 ? 3Na
分子量
1099.3 g/mol
保存条件
-20&#176;C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

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g/mol