Propafenone (SA-79) is an orally active sodium channel blocking agent and a beta-adrenoceptor (β-adrenergic receptor) antagonist. Propafenone offers a broad spectrum of activity in the treatment of cardiac arrhythmias.
Application of 10 µM propafenone decreases the Kv currents by 51%, as measured at +60 mV.[2]
[1] H M Bryson, et al. Drugs. 1993 Jan;45(1):85-130. [2] An JR, et al. Korean J Physiol Pharmacol. 2018 Sep;22(5):597-605.
















