Prolactin Human Recombinant Antagonist des 1-9, G129R produced in E.Coli is a single, non-glycosylated polypeptide chain containing 190 amino acids + an additional Ala at n-terminal and having a molecular mass of ~ 22 kDa.The Human Prolactin Antagonist is purified by proprietary chromatographic techniques.
Prolactin Human, Antagonist
目录号: GP20849纯度: >98%
Prolactin Antagonist Human Recombinant
| 规格 | 价格 | 库存 | 数量 | 操作 |
|---|---|---|---|---|
| 10μg | ¥700.00 | 现货 | 1 | |
| 50μg | ¥1,820.00 | 现货 | 1 | |
| 1mg | ¥44,100.00 | 现货 | 1 |
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Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
产品描述 Description
产品文档 Product Documents
Purity:>98%
Product Data
Purity
Greater than 95.0% as determined by gel filtration analysis.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Shipping Condition
Shipped at Room temp.
Synonyms
Mammotropin; Luteotropic hormone; Luteotropin; PRL.
Amino Acid Sequence
The a.a. sequence of the 1st 6 N-terminal a.a. was found to be Ala-Arg-Ser-Gln-Val-Thr.
Solubility
It is recommended to reconstitute the lyophilized Prolactin in sterile 0.4% NaHCO3 pH-8.5, not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability
Lyophilized Prolactin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Prolactin should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Biological Activity
Human Prolactin Antagonist was tested for its biological functionality in-vitro by inducing proliferation of Nb2 cells or Baf/3 cells that were stably transfected with Human Prolactin receptors. Prolactin Antagonist also interacts at 1:1 molar ratio with human prolactin receptor extracellular domain as documented by SEC and SPR (Biacore analysis).
Formulation
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.02% NaHCO3