Piperacetazine is a typical antipsychotic.1 It inhibits spontaneous motor activity and responding for food in rats, as well as potentiates hexobarbital-induced narcosis in mice. It also inhibits lysosome acidification, as well as viral entry (IC50 = <8.5 ?M), in Ebola-infected Huh7 cells.2 Formulations containing piperacetazine have been used in the treatment of schizophrenia.
1.Pitman-MoorePiperacetazine (Quide tablets)Clin. Pharmacol. Ther.10(5)749-754(1969) 2.Dyall, J., Nelson, E.A., DeWald, L.E., et al.Identification of combinations of approved drugs with synergistic activity against Ebola virus in cell culturesJ. Infect. Dis.218(Suppl 5)S672-S678(2018)