Phytoene desaturase-IN-1 is a potent phytoene desaturase (PDS) inhibitor (Kd: 65.9 μM) through π−π stacking effect with Phe301 residue. Phytoene desaturase-IN-1 shows broad spectrum of postemergence herbicidal activity. Phytoene desaturase-IN-1 induces PDS mRNA reduction, phytoene and reactive oxygen species (ROS) accumulation in albino leaves. Phytoene desaturase-IN-1 can be used in the area of agricultural production.
Phytoene desaturase-IN-1 (1b, 375−750 g/ha, 25 days) shows a broad spectrum of herbicidal activity against six kinds of weeds (including ECHCG, DIGSA, SETFA, ABUJU, AMARE, and ECLPR)[1].
Phytoene desaturase-IN-1 (750 g/ha, 14 days) down-regulates PDS mRNA level and induces phytoene accumulation, with the observed albino leaf phenotype[1].
Phytoene desaturase-IN-1 (750 g/ha, 3 days) induces ROS accumulation and regulates ROS-associated enzymes activity[1].