Phosphoglycolohydroxamic acid is a potent aldolase and triose-phosphate isomerase inhibitor. Phosphoglycolohydroxamic acid can be used in the research of antibacterial and antifungal area.
Phosphoglycolohydroxamic acid competitively inhibits rabbit muscle FDP-aldolase and chicken triosephosphate isomerase over a wide range pH[1].
References:
[1]. By DENNIS J. LEWI, et al. Phosphoglycollohydroxamic Acid : an Inhibitor of Class I and I1 Aldolasesand Triosephosphate Isomerase. A Potential Antibacterial and Antifungal Agent. J. Chem. Soc., Chem. Commun., 1973, 713-715.
[2]. Sabine Gavalda, et al. N-Sulfonyl hydroxamate derivatives as inhibitors of class II fructose-1,6-diphosphate aldolase. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5375-7.