Peptides

All-D Aβ (1-42) exhibits similar properites as the all-L Aβ. The peptide forms ion channels in lipid bilayers.

Fluorogenic (FRET) substrate for pro-memapsin-2 containing the β-secretase site of the Swedish mutation of APP, SEVNLDAEF.

This fluorescent (FRET) peptide substrate contains the wild-type amyloid precursor protein (APP) β-secretase cleavage site. Mca-SEVKMDAEFRK(Dnp)RR- amide has been used for assaying β-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). The results suggested that TOP is a potential β-secretase candidate and is involved in the processing of APP in vivo. See also L-1905.

Intramolecularly quenched fluorescent, presenilin-dependent substrate for assaying γ-secretase activity. The FRET substrate has been used for partial purification and characterization of γ-secretase from post-mortem human brain.

This peptide is a specifically designed negative control in studies with Abeta40. It is "scrambled", which means it contains the same amino acids as Abeta40, but in different order. Referring to studies by Yamin and coworkers, Teplow's Amyloid β-Protein (1-40) does not show a number of phenomena regularly observed with Abeta40 (fibril formation, oligomerization, toxicity to neurons) and furthermore has a relatively flat hydropathy profile, which can be an advantage in several studies, for example in order to avoid unspecific interaction with the cell membrane.

This peptide is a specifically designed negative control in studies with Abeta42. It is "scrambled", which means it contains the same amino acids as Abeta42, but in different order. Referring to studies by Yamin and coworkers, Teplow's Amyloid β-Protein (1-42) does not show a number of phenomena regularly observed with Abeta42 (fibril formation, oligomerization, toxicity to neurons) and furthermore has a relatively flat hydropathy profile, which can be an advantage in several studies, for example in order to avoid unspecific interaction with the cell membrane.

Fluorescent dye-labeled Aβ40, excitation at 649 nm, emission at 664 nm. Tide Fluor™ 5WS shows strong fluorescence and excellent photostability.

Fluorescent dye-labeled Aβ40, excitation at 749nm, emission at 775nm. Tide Fluor™ 7WS shows strong fluorescence and excellent photostability.

β-Amyloid (1-42), human TFA淀粉样蛋白 β 肽 (1-42) 人 TFA 是一种由 42 个氨基酸组成的肽。

百日咳毒素是一种基于蛋白质的 AB5 型外毒素，由百日咳博德特氏菌产生，可引起百日咳。

β-Amyloid 22-35 (Amyloid β-Protein (22-35))是一种由14个氨基酸组成的多肽片段，能够自发聚集形成β-折叠结构，并对海马神经元产生显著的细胞毒性作用。

β-Amyloid 1-16 (Amyloid β-Protein (1-16)) 是 ⋲-Amyloid 蛋白片段，参与金属结合。

β-Amyloid 29-40 (Amyloid beta-protein(29-40)) 是 Amyloid-β 的一个片段；肽。

β-Amyloid(10-35),amide是一种含有26个氨基酸的多肽，由β-Amyloid肽的10-35残基组成。β-Amyloid(10-35)是阿尔兹海默症淀粉样斑块(Alzheimer'sdisease)的主要组成成分。

β-Amyloid 1-28 (Amyloid β-Protein (1-28)) 是 β-Amyloid 蛋白片段，参与金属结合。

β-Amyloid(31-35)是具有神经毒性的天然β淀粉样肽的最短序列。

Beta-Amyloid(1-14),mouse,rat是Amyloid-β多肽的1-14片段。

β-Amyloid(1-42),ratTFA是由42个氨基酸组成的多肽，对海马切片有毒性，可用于阿尔兹海默症的研究。

β-amyloid(15-21)是β淀粉样肽的一个片段，在神经领域具有潜在的作用。

淀粉样蛋白 β Peptide (42-1)(human) 是淀粉样蛋白 β 的无活性形式；肽 (1-42)。

淀粉样蛋白 ⋲-肽 (1-40) 大鼠是淀粉样蛋白 β-肽的大鼠形式，它作为不溶性细胞外沉积物积聚在神经元周围，导致与阿尔茨海默病 (AD) 相关的老年斑。