Niacin-13C6

目录号: GC65072纯度: >98%同义词: 尼克酸-13C6,Nicotinic acid-13C6; Vitamin B3-13C6
Niacin-13C6 (Nicotinic acid-13C6) 是一种 13C 标记的 Niacin。Niacin (Nicotinic acid) 是维生素 B 家族中一员。

Niacin-13C6
Cas No.: 1189954-79-7
规格价格库存数量操作
1mg¥6,885.00现货
1

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产品描述 Description

Niacin-13C6 (Nicotinic acid-13C6) is the 13C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Bruckert E, et al. Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis. Atherosclerosis. 2010 Jun;210(2):353-61.
[3]. Wan P, et al. Pellagra: a review with emphasis on photosensitivity. Br J Dermatol. 2011 Jun;164(6):1188-200.
[4]. Ishii N, et al. Pellagra among chronic alcoholics: clinical and pathological study of 20 necropsy cases. J Neurol Neurosurg Psychiatry. 1981 Mar;44(3):209-15.

产品文档 Product Documents

化学性质Chemical Properties

CAS 号
1189954-79-7
同义词
尼克酸-13C6,Nicotinic acid-13C6; Vitamin B3-13C6
分子式
13C6H5NO2
分子量
129.07 g/mol
溶解性
DMSO : 50 mg/mL (387.39 mM; ultrasonic and warming and heat to 60°C); H<sub>2</sub>O : 10 mg/mL (77.48 mM; Need ultrasonic)
保存条件
Store at -20&#176;C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol