Nepitrin is a flavonoid glycoside that has been found in S. plebeia and has diverse biological activities.1,2,3 It protects lard from thermal oxidation when used at concentrations of 0.02 and 0.04%. Nepitrin inhibits carrageenin-induced edema and yeast-induced fever in rats.2 It decreases serum levels of triglycerides and LDL, as well as increases serum HDL levels, in a rat model of high-fat diet-induced atherosclerosis when administered at doses of 20 and 50 mg/kg.3
1.Weng, X.C., and Weng, W.Antioxidant activity of compounds isolated from Salvia plebiaFood Chem.71(4)489-493(2000) 2.Agarwal, O.P.The anti-inflammatory action of nepitrin, a flavonoidAgents Actions12(3)298-302(1982) 3.Devi, S., Rangra, N.K., Rawat, R., et al.Anti-atherogenic effect of Nepitrin-7-O-glucoside: A flavonoid isolated from Nepeta hindostana via acting on PPAR - α receptorSteroids165108770(2021)