N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium (DOTMA) is a cationic lipid. [1] It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro. [1] [2]
Reference:
[1]. Wang, X., Yu, B., Ren, W., et al. Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations. J. Control Release 172(3), 690-698 (2013).
[2]. Huang, Q.-D., Zhong, G.-X., Zhang, Y., et al. Cyclen-based cationic lipids for highly efficient gene delivery towards tumor cells. PLoS One 6(8), e23134 (2011).