GlpBio

Mca-P-Cha-G-Nva-HA-Dap(Dnp)-NH2 (trifluoroacetate salt)

目录号: GC47605纯度: >95.00%同义词: Mca-Pro-Cha-Gly-Nva-His-Ala-Dap(DNP)-NH2
A neuropeptide with diverse biological activities
Mca-P-Cha-G-Nva-HA-Dap(Dnp)-NH2 (trifluoroacetate salt)
Cas No.: N/A
规格价格库存数量操作
1 mg¥3,203.00现货
1
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文献被引

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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Mca-P-Cha-G-Nva-HA-Dap(Dnp)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26.1,2 Upon cleavage by MMP-1, MMP-3, or MMP-26, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.

1.Park, H.I., Turk, B.E., Gerkema, F.E., et al.Peptide substrate specificities and protein cleavage sites of human endometase/matrilysin-2/matrix metalloproteinase-26J. Biol. Chem.277(38)35168-35175(2002) 2.KnÄuper, V., Patterson, M.L., Gomis-RÜth, F.X., et al.The role of exon 5 in fibroblast collagenase (MMP-1) substrate specificity and inhibitor selectivityEur. J. Biochem.268(6)1888-1896(2001)

产品文档 Product Documents

Purity:>95.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
N/A
同义词
Mca-Pro-Cha-Gly-Nva-His-Ala-Dap(DNP)-NH2
SMILES
O=C([C@H]1N(C(CC2=CC(OC3=C2C=CC(OC)=C3)=O)=O)CCC1)N[C@@H](CC4CCCCC4)C(NCC(N[C@@H](CCC)C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CNC5=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C5)=O)C)=O)CC6=CNC=N6)=O)=O)=O.FC(F)(C(O)=O)F
分子式
C51H65N13O15.XCF3COOH
分子量
1100.1 g/mol
溶解性
Formic Acid: 1 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol