GlpBio

MARK4 inhibitor 3

目录号: GC73538纯度: >98.00%
MARK4 inhibitor 3（化合物23b）是MAPK4的抑制剂，IC50值为1.01μM。
MARK4 inhibitor 3
规格价格库存数量操作
5 mg¥1,530.00现货
1
10 mg¥2,430.00现货
1
25 mg¥4,860.00现货
1
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文献被引

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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

MAPK4 inhibitor 3 (compound 23b) is an inhibitor of MAPK4 with an IC50 value of 1.01 μM. MAPK4 inhibitor 3 inhibits cancer cells growth. MAPK4 inhibitor 3 can be used for research on cancer and tauopathies.

MAPK4 inhibitor 3 (1-20 μM, 24 h) inhibits Hela and U87MG growth with EC50 values of 2.52 μM and 4.22 μM, respectively[1].

References:
[1]. Maria Voura, et al. Synthesis, Structural Modification, and Bioactivity Evaluation of Substituted Acridones as Potent Microtubule Affinity-Regulating Kinase 4 Inhibitors. ACS Pharmacology & Translational Science 2023 6 (7), 1052-1074.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

分子式
C33H27FN4O3
分子量
546.59 g/mol
溶解性
DMSO : 125 mg/mL (228.69 mM; Need ultrasonic)
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol