MAO-B-IN-17 is a selective monoamine oxidase B (MAO-B) inhibitor with the IC50 value of 5.08 μM. MAO-B-IN-17 can be used in Parkinson’s disease research.
MAO-B-IN-17 (Compound 4j) (10 μM, 24 h) shows no cytotoxic effect on human neuroblastoma cells[1].
References:
[1]. Makito Yamada, et al. Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues. ACS Med. Chem. Lett. 2022.
















