lsocryptomerin is a membrane-active antifungal compound that can be isolated from Selaginella tamariscina. lsocryptomerin can depolarize fungal plasma membrane. lsocryptomerin also shows anticancer and antibacterial activities[1][2].
lsocryptomerin 抑制淋巴细胞增殖，对人肿瘤细胞系具有细胞毒性[1]。
lsocryptomerin (48 h) 具有抗真菌活性，对 C. albicans、T. beigelii 和 S. cerevisiae 的 MIC 值均为 18.11 μM[1]。
[1]. Lee J, et al. Isocryptomerin, a novel membrane-active antifungal compound from Selaginella tamariscina. Biochem Biops Res Commun. 2009 Feb 13;379(3):676-80.
[2]. Lee J, et al. Antibacterial and synergistic activity of isocryptomerin isolated from Selaginella tamariscina. J Microbiol Biotechnol. 2009 Feb;19(2):204-7.