L-ANAP is an unnatural amino acid with intrinsic fluorescence that can be genetically encoded into proteins.1 This technology allows incorporation of L-ANAP into virtually any site on a protein, providing a unique method for imaging biological processes in vivo.
1.Lee, H.S., Guo, J., Lemke, E.A., et al.Genetic incorporation of a small, environmentally sensitive, fluorescent probe into proteins in Saccharomyces cerevisiaeJ. Am. Chem. Soc.131(36)12921-12923(2009)