JWH 250 N-(4-hydroxypentyl) metabolite-d5

目录号: GC47514纯度: >99.00%
A neuropeptide with diverse biological activities

JWH 250 N-(4-hydroxypentyl) metabolite-d5
Cas No.: 1782062-60-5
规格价格库存数量操作
100 μg¥1,802.00现货
1
500 μg¥5,521.00现货
1
1 mg¥7,501.00现货
1

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产品描述 Description

JWH 250 N-(4-hydroxypentyl) metabolite-d5 contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 250 N-(4-hydroxypentyl) metabolite by GC- or LC-mass spectrometry. JWH 250 is a synthetic cannabinoid (CB) which potently activates both CB1 and CB2 receptors (Ki = 11 and 33 nM, respectively).1 It has been identified in herbal blends.2 JWH 250 N-(4-hydroxypentyl) metabolite is expected to be a cytochrome P450 phase I metabolite of JWH 250, detectable both in serum and urine.3,4,5

1.Huffman, J.W., Szklennik, P.V., Almond, A., et al.1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indolesBioorg. Med. Chem. Lett.15(18)4110-4113(2005) 2.Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y.Survey of current trends in the abuse of psychotropic substances and plants in JapanLeg. Med. (Tokyo)13(3)109-115(2011) 3.Wintermeyer, A., MÖller, I., Thevis, M., et al.In vitro phase I metabolism of the synthetic cannabimimetic JWH-018Anal. Bioanal. Chem.398(5)2141-2153(2010) 4.Zhang, Q., Ma, P., Cole, R.B., et al.Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MSAnalytical and Bioanalytical Chemistry3861345-1355(2006) 5.Sobolevsky, T., Prasolov, I., and Rodchenkov, G.Detection of JWH-018 metabolites in smoking mixture post-administration urineForensic Sci. Int.200(1-3)141-147(2010)

产品文档 Product Documents

Purity:>99.00%Appearance:A solution in methanol

化学性质Chemical Properties

CAS 号
1782062-60-5
SMILES
CC(O)CCCN1C2=C([2H])C([2H])=C([2H])C([2H])=C2C(C(CC3=C(OC)C=CC=C3)=O)=C1[2H]
分子式
C22H20D5NO3
分子量
356.5 g/mol
溶解性
DMF: 20 mg/ml,DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml,DMSO: 14 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol