JWH 200 7-hydroxyindole metabolite

JWH 200 is an aminoalkylindole that acts as a cannabinoid (CB) receptor agonist, binding the CB₁ receptor with high-affinity (IC₅₀ = 7.8-42 nM).^1,2 JWH 200 is one of several synthetic CBs which have been included in smoking mixtures.³ JWH 200 7-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 200 based on the metabolism of the closely related JWH 015 and JWH 018.^4,5

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