JWH 081 N-(4-hydroxypentyl) metabolite-d5 contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 081 N-(4-hydroxypentyl) metabolite by GC- or LC-MS. JWH 081 N-(4-hydroxypentyl) metabolite is an expected product of the phase I metabolism of JWH 081 , based on studies on the metabolism of the related synthetic cannabinoids JWH 018 and JWH 073 .1,2
1.Wintermeyer, A., MÖller, I., Thevis, M., et al.In vitro phase I metabolism of the synthetic cannabimimetic JWH-018Anal. Bioanal. Chem.398(5)2141-2153(2010)
2.Chimalakonda, K.C., Moran, C.L., Kennedy, P.D., et al.Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urineAnal. Chem.83(16)6381-6388(2011)
