Iopromide

目录号: GC32480纯度: >98.00%同义词: 碘普罗胺

A contrast reagent

Cas No.: 73334-07-3

规格	价格	库存	数量
5mg	¥350.00	现货	1
10mg	¥490.00	现货	1
25mg	¥840.00	现货	1
50mg	¥1,120.00	现货	1
100mg	¥1,540.00	现货	1
10mM (in 1mL DMSO)	¥426.00	现货	1

电话: 400-920-5774Email: sales@glpbio.cn

文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例

Nature
641, 529–536 (2025)
Nature
628, 630–638 (2024)
Nature
632, 686–694 (2024)
Nature
618, 1017–1023 (2023)
Nature
610, 366–372 (2022)
Cell
187(9):2288-2304 (2024)
Cell
183(7):1867-1883 (2020)
Science
388(6745) (2025)
Science
387(6739) (2025)
Science
387(6734) (2025)
Cell Research
35, 97–116 (2025)
Cell Research
34, 683–706 (2024)
Cell Research
33, 273–287 (2023)
Cell Research
33, 546–561 (2023)
Cell Research
33, 904–922 (2023)
Cell Research
31, 1291–1307 (2021)

产品描述 Description

Iopromide is a non-ionic, water-soluble X-ray contrast agent for intravascular administration.^1,2 Iopromide can cause acute kidney injury and is used in animal models of contrast-induced nephropathy.^3,4

1.Ahn, Y.H., Koh, Y.I., Kim, J.H., et al.The potential utility of iodinated contrast media (ICM) skin testing in patients with ICM hypersensitivityJ. Korean Med. Sci.30(3)245-251(2015) 2.Park, J.Y., Lee, S.K., Kim, J.Y., et al.A new micro-computed tomography-based high-resolution blood-brain barrier imaging technique to study ischemic strokeStroke45(8)2480-2484(2014) 3.Hassan, K., and Fadi, H.Is hypoalbuminemia a prognostic risk factor for contrast-induced nephropathy in peritoneal dialysis patients?Ther. Clin. Risk Manag.10787-795(2014) 4.Wang, N., Wei, R.b., Li, Q.p., et al.Renal Protective Effect of Probucol in Rats with Contrast-Induced Nephropathy and its Underlying MechanismMed. Sci. Monit.212886-2892(2015)

实验参考方法 Experimental Reference Method

Animal experiment:

Mice: Male C57/BL6J mice are randomly divided into 7 groups: control, diabetes mellitus (D), CIN, diabetes mellitus+CIN (DC), diabetes mellitus+Breviscapine (DB), CIN+Breviscapine (CIN+B) and diabetes mellitus+CIN+Breviscapine (DCB). After the model of diabetes mellitus is established, mice are prohibited drinking water for one night, and then mice are injected at a dose of 10 mL/kg iopromide via tail vein administration over the course of 1 minute. Then the mice are treated intragastrically with or without Breviscapine (10 mg/kg/d) for 4 weeks. Other mice groups except for Breviscapine treatment groups (DB, DCB and CIN+B) are administered the same volume of phosphate buffered solution intragastrically for 4 weeks. Then mice are sacrificed by an intraperitoneal injection of chloral hydrate[1].

References:

[1]. Jiang W, et al. Breviscapine attenuatted contrast medium-induced nephropathy via PKC/Akt/MAPK signalling in diabetic mice. Am J Transl Res. 2016 Feb 15;8(2):329-41.
[2]. McCormack PL, et al. Iobitridol: a review of its use as a contrast medium in diagnostic imaging. Clin Drug Investig. 2013 Feb;33(2):155-66.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号

73334-07-3

同义词

碘普罗胺

SMILES

O=C(C1=C(I)C(NC(COC)=O)=C(I)C(C(NCC(O)CO)=O)=C1I)N(CC(O)CO)C

分子式

C₁₈H₂₄I₃N₃O₈

分子量

791.11 g/mol

溶解性

DMSO : ≥ 150 mg/mL (189.61 mM)

保存条件

Store at -20°C

General tips

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。

Shipping Condition

评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

质量 (Mass)

体积 (Volume)

浓度 (Concentration)

分子量 (MW)

g/mol