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IL 18 Mouse Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 158 amino acids (36-192 a.a.)and having a molecular mass of 18.2kDa.The IL 18 is purified by proprietary chromatographic techniques.
| Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Interleukin-18; IL-18; IFN gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma. | ||
| Amino Acid Sequence | MNFGRLHCTT AVIRNINDQV LFVDKRQPVF EDMTDIDQSA SEPQTRLIIYMYKDSEVRGL AVTLSVKDSK MSTLSCKNKI ISFEEMDPPE NIDDIQSDLI FFQKRVPGHN KMEFESSLYEGHFLACQKED DAFKLILKKK DENGDKSVMF TLTNLHQS. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. | ||
| Formulation | The IL 18 protein solution (0.5mg/ml) contains PhosphateBuffered Saline (pH7.4). | ||
IL-18 is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.