Interferon-alpha 2b 20kd-Pegylated Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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Interferon-a 2b Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19269 Dalton. The PegylatedIFN-a 2b is produced by attaching a 20kDa mPEG-aldehyde to the N-terminal IFN alpha-2b. Interferon-a 2b is purified by proprietary chromatographic techniques.
| Purity | Greater than 97.0% as determined by SEC-HPLC. | Source | Escherichia Coli. |
| Phycical Appearance | Colorless, clear and transparent solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Interferon alpha 2b; IFNA; INFA2; MGC125764; MGC125765. | ||
| Stability | IFN alpha-2b PEG should be stored refrigerated at 2бу to 8°C . Vials should be kept in theirpackaging to protect from light until the time of use. Shaking and freezing should be avoided. | ||
| Biological Activity | The specific activity as determined in a viral resistance assay using VSV-WISH cells was found to be 3,000,000 IU/mg. | ||
| Formulation | IFN-a 2b is supplied in solution (1.48mg/ml)containing 20mM Acetate Buffer (pH 6.0), 0.8%NaCl and 0.005% Polysorbate 80. | ||
IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase.
The specific activity as determined in a viral resistance assay using VSV-WISH cells was found to be 3,000,000 IU/mg.
IFN alpha-2b PEG should be stored refrigerated at 2бу to 8°C . Vials should be kept in theirpackaging to protect from light until the time of use. Shaking and freezing should be avoided.