Homosalate (HMS, Homomenthyl salicylate) is an organic ultraviolet filter used in most sunscreens but has been reported to be toxic to marine organisms. Homosalate aggravates the invasion of human trophoblast cells as well as regulates intracellular signaling pathways including PI3K/AKT and MAPK pathways.
Extracellular vesicles (EVs) released by Homosalate‐treated cells enhance resistance to anchorage loss in another recipient epithelial tumour cell line.[2]
[1] Changwon Yang, et al. Environ Pollut. 2018 Dec;243(Pt B):1263-1273. [2] Grisard E, et al. J Extracell Vesicles. 2022 Jul;11(7):e12242.
















