Hexadecanal-d5 contains five deuterium atoms at the 15, 15', 16, 16 and 16 positions. It is intended for use as an internal standard for the quantification of hexadecanal by GC- or LC-mass spectrometry. Sphingosine-1-phosphate (S1P) is a potent bioactive phospholipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.1 Hexadecanal is the 16-carbon aldehyde analog of palmitic acid. It is produced from the irreversible cleavage of S1P by S1P lyase 1 and is a major component of plasmalogen.2,3
1.Leclercq, T.M., and Pitson, S.M.Cellular signalling by sphingosine kinase and sphingosine 1-phosphateIUBMB Life58467-472(2006)
2.Reiss, U., Oskouian, B., Zhou, J., et al.Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosisThe Journal of Biological Chemisty279(2)1281-1290(2004)
3.Pyne, S., and Pyne, N.J.Sphingosine 1-phosphate signalling in mammalian cellsBiochemistry Journal349385-402(2000)
