GlpBio

H-HoArg-OH

目录号: GA10611纯度: >97.00%同义词: 高精氨酸
H-HoArg-OH 是精氨酸同源物，是人骨和肝脏碱性磷酸酶的强抑制剂。
H-HoArg-OH
Cas No.: 156-86-5
规格价格库存数量操作
5g¥399.00现货
1
25g¥1,596.00现货
1
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文献被引

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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    31, 1291–1307 (2021)

产品描述 Description

H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.

It is found that H-HoArg-OH (L-homoarginine), a homologue of arginine, is a strong inhibitor of human bone and liver alkaline phosphatase while it has virtually no effect on intestinal and placental alkaline phosphatases unlike H-HoArg-OH which inhibits intestinal and placental alkaline phosphatases but not the liver and bone enzymes. These four tissues mentioned are the major contributors to the serum alkaline phosphatase[1]. It is also indicated that low levels of the endogenous amino acid H-HoArg-OH are linked to cardiovascular disease[2].

References:
[1]. Fishman W, et al. L-homoarginine; an inhibitor of serum "bone and liver" alkaline phosphatase. Clin Chim Acta. 1970 Aug;29(2):339-41.
[2]. Atzler D, et al. L-homoarginine and cardiovascular disease. Curr Opin Clin Nutr Metab Care. 2015 Jan;18(1):83-8.

产品文档 Product Documents

Purity:>97.00%

化学性质Chemical Properties

CAS 号
156-86-5
同义词
高精氨酸
化学名
(2S)-2-amino-6-(diaminomethylideneamino)hexanoic acid
SMILES
C(CCN=C(N)N)CC(C(=O)O)N
分子式
C7H16N4O2
分子量
188.2 g/mol
溶解性
H<sub>2</sub>O : 100 mg/mL (531.26 mM; Need ultrasonic); DMSO : &lt; 1 mg/mL (insoluble or slightly soluble)
保存条件
Store at 2-8°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol