GLP-1 (1-32) (bullfrog) (trifluoroacetate salt)

Glucagon-like peptide 1 (GLP-1) (1-32) is an endogenous incretin hormone.^[1] It increases intracellular cAMP levels using HEK293 cells expressing human GLP-1 receptor (GLP-1R; EC₅₀ = 0.051 nM). In vivo, GLP-1 (1-32) (30 mg/kg) reduces blood glucose levels in an oral glucose tolerance test (OGTT) in fasted mice.

References:
[1].Jiang, N., Su, D., Chen, D., et al.Discovery of a novel glucagon-like peptide-1 (GLP-1) analogue from bullfrog and investigation of its potential for designing GLP-1-based multiagonistsJ. Med. Chem.67(1)180-198(2024).