GlpBio

Meclofenamate sodium

目录号: GC38657纯度: >99.50%同义词: 甲氯灭酸钠,Meclofenamate sodium
A competitive inhibitor of COX-1 and -2
Meclofenamate sodium
Cas No.: 6385-02-0
规格价格库存数量操作
50mg¥450.00现货
1
100mg¥810.00现货
1
200mg¥1,350.00现货
1
10mM (in 1mL DMSO)¥495.00现货
1
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文献被引

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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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产品描述 Description

Meclofenamate is a time-dependent, non-specific competitive inhibitor of COX-1 and -2. The IC50 values for inhibition of human recombinant COX-1 and -2 are 1.5 and 9.7 ?M, respectively for instantaneous inhibition. However, the IC50 is much lower if pre-incubated with the enzyme.1

1.Laneuville, O., Breuer, D.K., DeWitt, D.L., et al.Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugsJ. Pharmacol. Exp. Ther.271(2)927-934(1994)

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
6385-02-0
同义词
甲氯灭酸钠,Meclofenamate sodium
SMILES
O=C(O[Na])C1=CC=CC=C1NC2=C(Cl)C=CC(C)=C2Cl
分子式
C14H10Cl2NNaO2
分子量
318.13 g/mol
溶解性
250mg/mL in DMSO
保存条件
4°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol