GlpBio

MMAF sodium

目录号: GC38397纯度: >98%同义词: Monomethylauristatin F sodium
COASDSData Sheet
An auristatin with anticancer activity
MMAF sodium
Cas No.: 1799706-65-2
规格价格库存数量操作
5mg¥720.00现货
1
10mg¥1,080.00现货
1
25mg¥1,620.00现货
1
50mg¥2,250.00现货
1
100mg¥3,060.00现货
1
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文献被引

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    187(9):2288-2304 (2024)
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产品描述 Description

MMAF is an auristatin with anticancer activity.1 It is cytotoxic to Karpas 299 anaplastic large cell lymphoma, H3396 breast carcinoma, and 786-O and Caki-1 renal carcinoma cells in vitro (IC50s = 119, 105, 257, and 200 nM, respectively), as well as in a panel of 11 lymphoma cell lines (IC50s = 34.8-164 nM).

1.Doronina, S.O., Mendelsohn, B.A., Bovee, T.D., et al.Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: Effects of linker technology on efficacy and toxicityBiconjug. Chem.17(1)114-124(2006)

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
1799706-65-2
同义词
Monomethylauristatin F sodium
SMILES
CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C([O-])=O)CC2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)NC)=O)=O)C.[Na+]
分子式
C39H64N5NaO8
分子量
753.94 g/mol
溶解性
DMSO: ≥ 200 mg/mL (265.27 mM)
保存条件
Store at -20°C,unstable in solution, ready to use.
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol