Rebaudioside E is one of the steviol glycosides of the diterpene derivative, which occurs naturally in the S. rebaudiana leaves [1]. Rebaudioside E is a high-intensity sweetener, which is used to reduce the contribution of sucrose and other high-energy sweeteners to excessive calorie intake [2]. Rebaudioside E has been widely used as a model compound for the direct study of the structure-sweetness relationship, and for the development of new non-calorie sweeteners[3]. Rebaudioside E has been widely used as an internal standard to optimize the conditions for high-performance liquid chromatography analysis in order to identify the related compounds[4].
References:
[1] Purkayastha S, Bhusari S, Pugh G, et al. In vitro metabolism of rebaudioside E under anaerobic conditions: comparison with rebaudioside A[J]. Regulatory Toxicology and Pharmacology, 2015, 72(3): 646-657.
[2] Chen L, Pan H, Cai R, et al. Bioconversion of stevioside to rebaudioside E using glycosyltransferase UGTSL2[J]. Applied biochemistry and biotechnology, 2021, 193(3): 637-649.
[3] Okonkwo C E, Adeyanju A A, Onyeaka H, et al. A review on rebaudioside M: The next generation steviol glycoside and noncaloric sweetener[J]. Journal of Food Science, 2024, 89(11): 6946-6965.
[4] Chen L, Cai R, Weng J, et al. Production of rebaudioside D from stevioside using a UGTSL2 Asn358Phe mutant in a multi‐enzyme system[J]. Microbial Biotechnology, 2020, 13(4): 974-983.
Rebaudioside E是二萜衍生物中的一种甜菊糖苷，天然存在于S. rebaudiana叶片中[1]。Rebaudioside E是一种高甜度甜味剂，用于减少蔗糖和其他高热量甜味剂对过量热量摄入的贡献[2]。Rebaudioside E已被广泛用作直接研究结构-甜度关系的模型化合物，并用于开发新型无热量甜味剂[3]。Rebaudioside E已被广泛用作内标，以优化高效液相色谱分析条件，从而鉴定相关化合物[4]。